Evidence map›Paper›PMID 9604048›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA1997

Associations of vitamin C, calcium and protein with bone mass in postmenopausal Mexican American women.

M C Wang, M Luz Villa, R Marcus, J L Kelsey

Abstract read
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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Pooled it
  2. Trial
  3. Effect of antioxidants combined to resistance training on BMD in elderly women: a pilot study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2009
    Trial
  4. Review
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  6. A Structural Equation Modelling Approach to Determine Factors of Bone Mineral Density in Korean Women.International journal of environmental research and public health · 2021
    Article
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  12. Observational
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  15. Protective effect of high protein and calcium intake on the risk of hip fracture in the Framingham offspring cohort.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2010
    Article
  16. Is protein intake associated with bone mineral density in young women?The American journal of clinical nutrition · 2010
    Article
  17. Bone mineral density in post-menopausal female subjects is associated with serum antioxidant carotenoids.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

M C WangDepartment of Health Research and Policy, Stanford University School of Medicine, California 94305-5092, USA. maychoo@eland.stanford.edu
M Luz Villa
R Marcus
J L Kelsey
Stanford University · USGeriatric Research Education and Clinical Center · USStanford Health Care · US

Funding

OSTEOPOROSIS AND FALLS IN MEXICAN-AMERICAN ELDERSR01AG010454 · NIA · STANFORD UNIVERSITY · PI KELSEY, JENNIFER · 1991 to 1995
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NIA NIH HHS 1RO1AG10454 DK09003
6 · The paper itself

Abstract

We investigated the associations of vitamin C, calcium and protein intakes with bone mass at the femoral neck and lumbar spine in postmenopausal Mexican American women. Bone mass was measured by dual-energy X-ray absorptiometry (DXA) and expressed as areal (BMD, g/cm2) and volumetric (bone mineral apparent density or BMAD, g/cm3) bone mineral density. Diet was assessed using a modified version of the National Cancer Institute Food Questionnaire, which was administered by trained bilingual interviewers familiar with Mexican dietary practices. Data gathered from 125 subjects were analyzed using multiple linear regression analysis with age, body mass index (BMI), acculturation, years of estrogen use, physical activity, total energy intake, and the nutrient of interest as independent variables. Neither calcium nor calcium/protein ratio was associated with bone mineral density. There was evidence of a positive association between dietary vitamin C intake and femoral neck BMD (beta = 0.0002 g/cm2 per mg/day, SE = 0.00006, p < 0.05), but vitamin C was not associated with lumbar spine bone mass. Further investigation of the role of vitamin C in skeletal health is warranted.

Indexed as

Bone DensityMexican AmericansAgedAged, 80 and overAscorbic AcidCalcium, DietaryCross-Sectional StudiesDietary ProteinsEnergy IntakeFemaleFemur NeckHumansLumbar VertebraeMiddle AgedPostmenopauseRegression AnalysisAscorbic AcidCalcium, DietaryDietary Proteins

Identifiers

PMID9604048
OpenAlexW2020823775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.