ArticleInfection and immunity1998
Secreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells.
Article in Infection and immunity, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
29 citing papers in PubMed.
- Lectin-Fc(IgG2a) fusion proteins binding to the cell wall ofMicrobiology spectrum · 2026Article
- Article
- Extracellular vesicles from bacteria and fungi: mechanistic insights and implications for urinary tract infections.Extracellular vesicles and circulating nucleic acids · 2025Review
- Sequence Variation of Candida albicans Sap2 Enhances Fungal Pathogenicity via Complement Evasion and Macrophage M2-Like Phenotype Induction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- A C. albicans TRAPP Complex-Associated Gene Contributes to Cell Wall Integrity, Hyphal and Biofilm Formation, and Tissue Invasion.Microbiology spectrum · 2023Article
- Aspartic Proteases and Major Cell Wall Components inFrontiers in cellular and infection microbiology · 2017Article
- Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis.Infection and immunity · 2015Article
- Vhs2 is a novel regulator of septin dynamics in budding yeast.Cell cycle (Georgetown, Tex.) · 2014Article
- Human serum promotes Candida albicans biofilm growth and virulence gene expression on silicone biomaterial.PloS one · 2013Article
- The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity.Infection and immunity · 2010Article
- Canadian clinical practice guidelines for invasive candidiasis in adults.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2010Article
- Transcriptional responses of candida albicans to epithelial and endothelial cells.Eukaryotic cell · 2009Article
- Basidiomycete metabolites attenuate virulence properties of Candida albicans in vitro.Mycoses · 2008Article
- Candida albicans cell wall proteins.Microbiology and molecular biology reviews : MMBR · 2008Review
- Absent reduction by HIV protease inhibitors of Candida albicans adhesion to endothelial cells.Mycoses · 2007Article
- Phospholipase and proteinase activities of clinical isolates of Candida from immunocompromised patients.Mycopathologia · 2006Article
- Candida albicans Ecm33p is important for normal cell wall architecture and interactions with host cells.Eukaryotic cell · 2006Article
- Candida albicans-secreted aspartic proteinases modify the epithelial cytokine response in an in vitro model of vaginal candidiasis.Infection and immunity · 2005Article
- Differential expression of secretory aspartyl proteinase genes (SAP1-10) in oral Candida albicans isolates with distinct karyotypes.Journal of clinical microbiology · 2004Article
- Cdc42p GTPase regulates the budded-to-hyphal-form transition and expression of hypha-specific transcripts in Candida albicans.Eukaryotic cell · 2004Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The endothelial cell interactions of homozygous null mutants of Candida albicans that were deficient in secreted aspartyl proteinase 1 (Sap1), Sap2, or Sap3 were investigated. Only Sap2 was found to contribute to the ability of C. albicans to damage endothelial cells and stimulate them to express E-selectin. None of the Saps studied appears to play a role in C. albicans adherence to endothelial cells.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.