Evidence map›Paper›PMID 9596777›Full record

ArticleInfection and immunity1998

Extracellular release of antigenic proteins by Helicobacter pylori.

P Cao, M S McClain, M H Forsyth, T L Cover

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Infection and immunity, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 94 citations in OpenAlex.

  1. Trial
  2. Review
  3. How Long Will It Take to Launch an EffectiveInfection and drug resistance · 2023
    Review
  4. Journal of clinical medicine · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Analysis of cagA in Helicobacter pylori strains from Colombian populations with contrasting gastric cancer risk reveals a biomarker for disease severity.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2011
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

P CaoDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2605, USA.
M S McClain
M H Forsyth
T L Cover
Office of Infectious Diseases · USVanderbilt University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jin Chen · 1995 to 2026
$172.8M
Structure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2026
$8.3M
NCI NIH HHS CA68485NCI NIH HHS P30 CA068485NIAID NIH HHS AI39657NIAID NIH HHS R01 AI039657
6 · The paper itself

Abstract

Screening a Helicobacter pylori genomic library with antisera raised against H. pylori broth culture supernatant resulted in the identification of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-rich 28-kDa protein (designated HcpA). H. pylori antigens may be released into the extracellular space by multiple mechanisms, including specific secretion pathways, autolysis, and membrane vesicle formation.

Indexed as

Escherichia coli ProteinsMembrane Transport ProteinsAmino Acid SequenceAntigens, BacterialBacterial ProteinsGenomic LibraryHeat-Shock ProteinsHelicobacter pyloriHemolysin ProteinsHSP70 Heat-Shock ProteinsLipoproteinsMolecular Sequence DataPlasmidsSequence Analysis, DNASequence Homology, Amino AcidAntigens, BacterialBacterial ProteinsdnaK protein, E coliEscherichia coli ProteinsHcp protein, Vibrio choleraeHeat-Shock ProteinsHemolysin ProteinsHSP70 Heat-Shock ProteinsHspB protein, Helicobacter pyloriLipoproteinsLpp20 protein, Helicobacter pyloriMembrane Transport ProteinsmsrA protein, Staphylococcus epidermidis

Identifiers

PMID9596777
PMCPMC108299
OpenAlexW1786752461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.