ArticleThe Plant cell1998
BiP and calreticulin form an abundant complex that is independent of endoplasmic reticulum stress
Article in The Plant cell, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 79 citations in OpenAlex.
- Macrophages release neuraminidase and cleaved calreticulin for programmed cell removal.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- From the archives: Cold acclimation by plastid translation, metabolic allocation, and plant defense, and functions of a BiP-calreticulin complex.The Plant cell · 2023Article
- The K/HDEL receptor does not recycle but instead acts as a Golgi-gatekeeper.Nature communications · 2023Article
- A viral movement protein co-opts endoplasmic reticulum luminal-binding protein and calreticulin to promote intracellular movement.Plant physiology · 2023Article
- Design principles for the glycoprotein quality control pathway.PLoS computational biology · 2021Article
- Comparison of the Agronomic, Cytological, Grain Protein Characteristics, as Well as Transcriptomic Profile of Two Wheat Lines Derived From Wild Emmer.Frontiers in genetics · 2021Article
- CRISPR/Cas9 and Transgene Verification of Gene Involvement in Unfolded Protein Response and Recombinant Protein Production in Barley Grain.Frontiers in plant science · 2021Article
- Protein Quality Control in the Endoplasmic Reticulum of Plants.Annual review of plant biology · 2018Review
- Physiology and molecular biology of plants : an international journal of functional plant biology · 2016Article
- A role for sigma receptors in stimulant self-administration and addiction.Behavioural pharmacology · 2016Review
- Occurrence of calreticulin during the exchange of nucleohistones into protamine-type proteins in Chara vulgaris spermiogenesis.Protoplasma · 2013Article
- The secreted plant N-glycoproteome and associated secretory pathways.Frontiers in plant science · 2012Article
- Antigen retrieval to improve the immunocytochemistry detection of sigma-1 receptors and ER chaperones.Histochemistry and cell biology · 2011Article
- A Role for Sigma Receptors in Stimulant Self Administration and Addiction.Pharmaceuticals (Basel, Switzerland) · 2011Article
- Article
- Control of the pattern-recognition receptor EFR by an ER protein complex in plant immunity.The EMBO journal · 2009Article
- Specific ER quality control components required for biogenesis of the plant innate immune receptor EFR.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Temporal global expression data reveal known and novel salicylate-impacted processes and regulators mediating powdery mildew growth and reproduction on Arabidopsis.Plant physiology · 2009Article
- A novel methyltransferase methylates Cucumber mosaic virus 1a protein and promotes systemic spread.Journal of virology · 2008Article
- Over-expression of calcium-dependent protein kinase 13 and calreticulin interacting protein 1 confers cold tolerance on rice plants.Molecular genetics and genomics : MGG · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BiP is found in association with calreticulin, both in the presence and absence of endoplasmic reticulum stress. Although the BiP-calreticulin complex can be disrupted by ATP, several properties suggest that the calreticulin associated with BiP is neither unfolded nor partially or improperly folded. (1) The complex is stable in vivo and does not dissociate during 8 hr of chase. (2) When present in the complex, calreticulin masks epitopes at the C terminus of BiP that are not masked when BiP is bound to an assembly-defective protein. And (3) overproduction of calreticulin does not lead to the recruitment of more BiP into complexes with calreticulin. The BiP-calreticulin complex can be disrupted by low pH but not by divalent cation chelators. When the endoplasmic reticulum retention signal of BiP is removed, complex formation with calreticulin still occurs, and this explains the poor secretion of the truncated molecule. Gel filtration experiments showed that BiP and calreticulin are present in distinct high molecular weight complexes in which both molecules interact with each other. The possible functions of this complex are discussed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.