ArticleNeurosurgical review1998
High amino acid uptake in a low-grade desmoplastic infantile ganglioglioma in a 14-year-old patient.
Article in Neurosurgical review, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- Desmoplastic infantile and non-infantile ganglioglioma. Review of the literature.Neurosurgical review · 2010Review
- A report of a desmoplastic non-infantile ganglioglioma in a 6-year-old boy with review of the literature.Neurosurgical review · 2009Article
- Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2009Article
- A report of a desmoplastic ganglioglioma in a 12-year-old girl with review of the literature.Journal of neuro-oncology · 2006Article
- [11C]-Methionine PET: dysembryoplastic neuroepithelial tumours compared with other epileptogenic brain neoplasms.Journal of neurology, neurosurgery, and psychiatry · 2005Article
- Therapeutic strategies and management of desmoplastic infantile ganglioglioma: two case reports and literature overview.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2003Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amino acid uptake is higher in high-grade than in low-grade gliomas; this is the rationale for using radioactively labelled amino acids for the non-invasive grading of brain neoplasms. We present a 14-year-old boy with a low-grade desmoplastic infantile ganglioglioma (DIG) that exhibited marked contrast enhancement on magnetic resonance imaging (MRI), but no signs of infiltration and only minimal surrounding edema. In this benign neoplasm the relative uptake of the radioactively labelled amino acid I-123-alpha-methyl tyrosine (IMT), determined using single-photon emission computed tomography (SPECT), was 3.24; it was considerably higher than that of eleven other pretherapeutic low-grade gliomas where it ranged from 1.06 to 1.94 and also markedly above that average value of 2.37 found in 20 high-grade gliomas. This case report illustrates that results from emission tomography with radioactively labelled amino acids must be interpreted with caution, particularly when rare tumor entities are considered in view of uncommon clinical or radiological findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.