ArticleMolecular and cellular biology1998
p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.
Article in Molecular and cellular biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 92 citations in OpenAlex.
- The oligogenic inheritance test GCOD detects risk genes and their interactions in congenital heart defects.Genome research · 2026Article
- Functional networks of the human bromodomain-containing proteins.Frontiers in bioinformatics · 2022Article
- mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution.Nature structural & molecular biology · 2021Article
- Update and Potential Opportunities in CBP [Cyclic Adenosine Monophosphate (cAMP) Response Element-Binding Protein (CREB)-Binding Protein] Research Using Computational Techniques.The protein journal · 2021Review
- Altered ARID1A expression in colorectal cancer.BMC cancer · 2020Article
- ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells.Clinical epigenetics · 2019Article
- BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors.Nature communications · 2019Article
- Arid1a regulates insulin sensitivity and lipid metabolism.EBioMedicine · 2019Article
- Article
- WeSME: uncovering mutual exclusivity of cancer drivers and beyond.Bioinformatics (Oxford, England) · 2017Article
- Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Seminars in cancer biology · 2015Review
- Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme.Nature communications · 2015Article
- A rationale to target the SWI/SNF complex for cancer therapy.Trends in genetics : TIG · 2014Review
- Article
- Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators.Genome research · 2013Article
- Promoter hypermethylation of ARID1A gene is responsible for its low mRNA expression in many invasive breast cancers.PloS one · 2013Article
- ARID1A mutations in cancer: another epigenetic tumor suppressor?Cancer discovery · 2013Review
- An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer.Oncogene · 2012Article
- Highly parallel identification of essential genes in cancer cells.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Bright/ARID3A contributes to chromatin accessibility of the immunoglobulin heavy chain enhancer.Molecular cancer · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
p300 and the closely related CREB binding protein (CBP) are transcriptional adaptors that are present in intracellular complexes with TATA binding protein (TBP) and bind to upstream activators including p53 and nuclear hormone receptors. They have intrinsic and associated histone acetyltransferase activity, suggesting that chromatin modification is an essential part of their role in regulating transcription. Detailed characterization of a panel of antibodies raised against p300/CBP has revealed the existence of a 270-kDa cellular protein, p270, distinct from p300 and CBP but sharing at least two independent epitopes with p300. The subset of p300/CBP-derived antibodies that cross-reacts with p270 consistently coprecipitates a series a cellular proteins with relative molecular masses ranging from 44 to 190 kDa. Purification and analysis of various proteins in this group reveals that they are components of the human SWI/SNF complex and that p270 is an integral member of this complex.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.