ArticleThe EMBO journal1998
Cell cycle modulation of protein-DNA interactions at a human replication origin.
Article in The EMBO journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed, 65 citations in OpenAlex.
- DNA-protein interaction dynamics at the Lamin B2 replication origin.Cell cycle (Georgetown, Tex.) · 2015Article
- The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression.Genes & development · 2012Article
- Homeotic proteins participate in the function of human-DNA replication origins.Nucleic acids research · 2010Article
- Genomic study of replication initiation in human chromosomes reveals the influence of transcription regulation and chromatin structure on origin selection.Molecular biology of the cell · 2010Article
- Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins.The EMBO journal · 2009Article
- Chromatin fine structure of the c-MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Functional interactions of DNA topoisomerases with a human replication origin.The EMBO journal · 2007Article
- Small-molecule-based identification of dynamic assembly of E2F-pocket protein-histone deacetylase complex for telomerase regulation in human cells.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
- Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis.Molecular and cellular biology · 2004Article
- Defined sequence modules and an architectural element cooperate to promote initiation at an ectopic mammalian chromosomal replication origin.Molecular and cellular biology · 2004Article
- Modular structure of the human lamin B2 replicator.Molecular and cellular biology · 2004Article
- Long-term transgene expression in proliferating cells mediated by episomally maintained high-capacity adenovirus vectors.Journal of virology · 2004Article
- Localization of proteins bound to a replication origin of human DNA along the cell cycle.The EMBO journal · 2003Article
- Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression.The EMBO journal · 2003Article
- Is DNA sequence sufficient to specify DNA replication origins in metazoan cells?Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2003Review
- Cell cycle-dependent regulation of the association between origin recognition proteins and somatic cell chromatin.The EMBO journal · 2002Article
- Mammalian Orc1 protein is selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle.Molecular and cellular biology · 2002Article
- Involvement of cellular double-stranded DNA break binding proteins in processing of the recombinant adeno-associated virus genome.Journal of virology · 2001Article
- Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein-Barr virus.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus.The EMBO journal · 2001Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We followed the variations of protein-DNA interactions occurring in vivo over the early firing replication origin located near the human lamin B2 gene, in IMR-90 cells synchronized in different moments of the cell cycle. In G0 phase cells no protection is present; as the cells progress in G1 phase an extended footprint covering over 100 bp appears, particularly marked at the G1/S border. As the cells enter S phase the protection shrinks to 70 bp and remains unchanged throughout this phase. In mitosis the protection totally disappears, only to reappear in its extended form as the cells move into the next G1. These variations are reminiscent of those corresponding to the formation of the pre- and post-replicative complexes described in yeast and Xenopus cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.