ArticleJournal of virology1998
A recombinant classical swine fever virus stably expresses a marker gene.
Article in Journal of virology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 22 citations in OpenAlex.
- Establishment of a superinfection exclusion method for pestivirus titration using a recombinant reporter pestiviruses.The Journal of veterinary medical science · 2024Article
- Review
- Characterization of a Cytopathogenic Reporter CSFV.Viruses · 2021Article
- Development of a High-Throughput Serum Neutralization Test Using Recombinant Pestiviruses Possessing a Small Reporter Tag.Pathogens (Basel, Switzerland) · 2020Article
- Characterization of Recombinant Flaviviridae Viruses Possessing a Small Reporter Tag.Journal of virology · 2018Article
- In vitro adaptation and genome analysis of a sub-subgenotype 2.1c isolate of classical swine fever virus.Virus genes · 2016Article
- Generation and characterization of a hepatitis C virus NS3 protease-dependent bovine viral diarrhea virus.Journal of virology · 2000Article
- Cytopathogenic and noncytopathogenic RNA replicons of classical swine fever virus.Journal of virology · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gene coding for bacterial chloramphenicol acetyltransferase (CAT) was inserted in frame into the viral Npro gene of the full-length cDNA clone pA187-1 of the classical swine fever virus (CSFV) strain Alfort/187. RNA transcribed in vitro from the resulting plasmid was transfected into SK-6 porcine kidney cells. Infectious progeny virus vA187-CAT recovered from transfected cells had growth characteristics indistinguishable from those of parental virus vA187-1. In cells infected with vA187-CAT the predicted fusion protein, CAT-Npro, was detected, and it retained the enzymatic activities of both CAT and Npro. The CAT gene remained stably inserted in the viral genome after 10 virus passages. Thus, marker virus vA187-CAT represents a useful tool for quantitative analysis of viral replication and gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.