Evidence map›Paper›PMID 9572680›Full record

ArticleNeurochemical research1998

Mycobacterium leprae binds to a 25-kDa phosphorylated glycoprotein of human peripheral nerve.

L M Suneetha, P R Satish, R J Korula, S K Suneetha, C K Job, A S Balasubramanian

Abstract read
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In one paragraph

Article in Neurochemical research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L M SuneethaDepartment of Neurological Sciences, Christian Medical College and Hospital, Vellore, TN, India.
P R Satish
R J Korula
S K Suneetha
C K Job
A S Balasubramanian

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium leprae, the causative agent of leprosy, specifically invades and destroys the peripheral nerve, which results in the main clinical manifestation of the disease. Little is known about the bacteria-nerve protein interaction. We show in the present work that M leprae binds to a 25 kDa glycoprotein from human peripheral nerve. This protein is phosphorylatable and it binds to lectins which have alpha-mannose specificity. This M leprae-protein interaction could be of importance in the pathogenesis of leprosy.

Indexed as

AutoradiographyBacterial ProteinsElectrophoresis, Polyacrylamide GelEscherichia coliGlycoproteinsHumansLectinsMolecular WeightMycobacterium bovisMycobacterium lepraeNerve Tissue ProteinsPhosphorylationProtein BindingTibial NerveBacterial ProteinsGlycoproteinsLectinsNerve Tissue Proteins

Identifiers

PMID9572680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.