ArticleMolecular and cellular biology1998
Yeast RNA polymerase II transcription in vitro is inhibited in the presence of nucleotide excision repair: complementation of inhibition by Holo-TFIIH and requirement for RAD26.
Article in Molecular and cellular biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Transcriptional consequences of XPA disruption in human cell lines.DNA repair · 2017Article
- Preparation of efficient excision repair competent cell-free extracts from C. reinhardtii cells.PloS one · 2014Article
- Tfb5 is partially dispensable for Rad26 mediated transcription coupled nucleotide excision repair in yeast.DNA repair · 2007Article
- The comings and goings of nucleotide excision repair factors on damaged DNA.The EMBO journal · 2003Article
- Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation.Molecular and cellular biology · 2002Article
- Repair of damaged DNA by Arabidopsis cell extract.The Plant cell · 2002Article
- Local UV-induced DNA damage in cell nuclei results in local transcription inhibition.EMBO reports · 2001Article
- UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Rous-Whipple Award Lecture. Nucleotide excision repair and cancer predisposition: A journey from man to yeast to mice.The American journal of pathology · 2000Article
- Excision repair at the level of the nucleotide in the upstream control region, the coding sequence and in the region where transcription terminates of the Saccharomyces cerevisiae MFA2 gene and the role of RAD26.Nucleic acids research · 2000Article
- The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repair.Molecular biology of the cell · 1999Article
- Ubiquitination of RNA polymerase II large subunit signaled by phosphorylation of carboxyl-terminal domain.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes.Molecular biology of the cell · 1999Article
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3 authors at 1 institution in 1 country.
Funding
Abstract
The Saccharomyces cerevisiae transcription factor IIH (TFIIH) is essential both for transcription by RNA polymerase II (RNAP II) and for nucleotide excision repair (NER) of damaged DNA. We have established cell extracts which support RNAP II transcription from the yeast CYC1 promoter or NER of transcriptionally silent damaged DNA on independent plasmid templates and substrates. When plasmid templates and substrates for both processes are simultaneously incubated with these extracts, transcription is significantly inhibited. This inhibition is strictly dependent on active NER and can be complemented with purified holo-TFIIH. These results suggest that in the presence of active NER, TFIIH is preferentially mobilized from the basal transcription machinery for use in NER. Inhibition of transcription in the presence of active NER requires the RAD26 gene, the yeast homolog of the human Cockayne syndrome group B gene (CSB).
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