Molecular identity of the outwardly rectifying, swelling-activated anion channel: time to reevaluate pICln.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

23 citing papers in PubMed.

1. Trends in volume-regulated anion channel (VRAC) research: visualization and bibliometric analysis from 2014 to 2022.Frontiers in pharmacology · 2023
   Article
2. LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology.American journal of physiology. Cell physiology · 2021
   Article
3. A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel.The Journal of general physiology · 2019
   Review
4. Intracellular and extracellular loops of LRRC8 are essential for volume-regulated anion channel function.The Journal of general physiology · 2018
   Article
5. Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR).Pflugers Archiv : European journal of physiology · 2016
   Review
6. Metabolic perturbations of kidney and spleen in murine cerebral malaria: (1)H NMR-based metabolomic study.PloS one · 2013
   Article
7. The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume.The Journal of biological chemistry · 2011
   Article
8. Mechanisms of ATP release, the enabling step in purinergic dynamics.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2011
   Review
9. Role of pICLn in methylation of Sm proteins by PRMT5.The Journal of biological chemistry · 2009
   Article
10. Anion channels in astrocytes: biophysics, pharmacology, and function.Glia · 2006
    Review
11. Proteolytic modification of swelling-activated Cl- current in LNCaP prostate cancer epithelial cells.Journal of bioenergetics and biomembranes · 2002
    Article
12. Blocking swelling-activated chloride current inhibits mouse liver cell proliferation.The Journal of physiology · 2001
    Article
13. Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD).The Journal of physiology · 2001
    Review
14. Functional inhibition of native volume-sensitive outwardly rectifying anion channels in muscle cells and Xenopus oocytes by anti-ClC-3 antibody.The Journal of physiology · 2001
    Article
15. Pharmacological characterization of volume-sensitive, taurine permeable anion channels in rat supraoptic glial cells.British journal of pharmacology · 2000
    Article
16. Hyposmotically activated chloride channels in cultured rabbit non-pigmented ciliary epithelial cells.The Journal of physiology · 1999
    Article
17. Effects of anion channel antagonists in canine colonic myocytes: comparative pharmacology of Cl-, Ca2+ and K+ currents.British journal of pharmacology · 1999
    Article
18. Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.The Journal of physiology · 1999
    Article
19. A serine residue in ClC-3 links phosphorylation-dephosphorylation to chloride channel regulation by cell volume.The Journal of general physiology · 1999
    Article
20. Recombinant pICln forms highly cation-selective channels when reconstituted into artificial and biological membranes.The Journal of general physiology · 1998
    Article

Corrections and comments

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Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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