ArticleGenetics1998
Molecular genetic dissection of mouse unconventional myosin-VA: tail region mutations.
Article in Genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed.
- Myosin-5a facilitates stress granule formation by interacting with G3BP1.Cellular and molecular life sciences : CMLS · 2024Article
- Article
- Differential Myosin 5a splice variants in innervation of pelvic organs.Frontiers in physiology · 2023Article
- Myosin 5a in the Urinary Bladder: Localization, Splice Variant Expression, and Functional Role in Neurotransmission.Frontiers in physiology · 2022Article
- LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade.Life science alliance · 2021Article
- Unconventional Myosins: How Regulation Meets Function.International journal of molecular sciences · 2019Review
- Exploring the iceberg: Prospects of coordinated myosin V and actin assembly functions in transport processes.Small GTPases · 2019Review
- Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.Genome research · 2015Article
- A Hypothesis for Examining Skeletal Muscle Biopsy-Derived Sarcolemmal nNOSμ as Surrogate for Enteric nNOSα Function.Frontiers in medicine · 2015Article
- Structural basis of myosin V Rab GTPase-dependent cargo recognition.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Identification and characterization of multiple novel Rab-myosin Va interactions.Molecular biology of the cell · 2013Article
- More than just a cargo adapter, melanophilin prolongs and slows processive runs of myosin Va.The Journal of biological chemistry · 2013Article
- Functions of class V myosins in neurons.The Journal of biological chemistry · 2013Review
- Structural basis of cargo recognitions for class V myosins.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.PloS one · 2013Article
- Full-length myosin Va exhibits altered gating during processive movement on actin.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Myosin Va plays a key role in nitrergic neurotransmission by transporting nNOSα to enteric varicosity membrane.American journal of physiology. Gastrointestinal and liver physiology · 2011Article
- A role for myosin Va in cerebellar plasticity and motor learning: a possible mechanism underlying neurological disorder in myosin Va disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Whole-genome SNP association in the horse: identification of a deletion in myosin Va responsible for Lavender Foal Syndrome.PLoS genetics · 2010Article
- Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin.PLoS genetics · 2009Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
We used an RT-PCR-based sequencing approach to identify the mutations responsible for 17 viable dilute alleles, a mouse-coat-color locus encoding unconventional myosin-VA. Ten of the mutations mapped to the MyoVA tail and are reported here. These mutations represent the first extensive collection of tail mutations reported for any unconventional mammalian myosin. They identify sequences important for tail function and identify domains potentially involved in cargo binding and/or proper folding of the MyoVA tail. Our results also provide support for the notion that different myosin tail isoforms produced by alternative splicing encode important cell-type-specific functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.