ReviewGenetics1998
DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiae.
Review in Genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 74 citations in OpenAlex.
- Trajectory and uniqueness of mutational signatures in yeast mutators.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Hydrogen peroxide, a potent inducer of global genomic instability.Current genetics · 2019Review
- New Possibilities on the Horizon: Genome Editing Makes the Whole Genome Accessible for Changes.Frontiers in plant science · 2019Review
- Review
- DNA mismatch repair preferentially protects genes from mutation.Genome research · 2018Article
- Effect of mutation mechanisms on variant composition and distribution in Caenorhabditis elegans.PLoS computational biology · 2017Article
- Epigenetic reduction of DNA repair in progression to gastrointestinal cancer.World journal of gastrointestinal oncology · 2015Article
- Preservation of genetic and regulatory robustness in ancient gene duplicates of Saccharomyces cerevisiae.Genome research · 2014Article
- Novel diet-related mouse model of colon cancer parallels human colon cancer.World journal of gastrointestinal oncology · 2014Article
- Precise estimates of mutation rate and spectrum in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Mutation rates, spectra, and genome-wide distribution of spontaneous mutations in mismatch repair deficient yeast.G3 (Bethesda, Md.) · 2013Article
- Estimating selection on synonymous codon usage from noisy experimental data.Molecular biology and evolution · 2013Article
- The roles of whole-genome and small-scale duplications in the functional specialization of Saccharomyces cerevisiae genes.PLoS genetics · 2013Article
- Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Article
- The mother enrichment program: a genetic system for facile replicative life span analysis in Saccharomyces cerevisiae.Genetics · 2009Article
- Article
- A genome-wide view of the spectrum of spontaneous mutations in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Evidence for mutation showers.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes.BMC immunology · 2005Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To help elucidate the mechanisms involved in spontaneous mutagenesis, DNA sequencing has been applied to characterize the types of mutation whose rates are increased or decreased in mutator or antimutator strains, respectively. Increased spontaneous mutation rates point to malfunctions in genes that normally act to reduce spontaneous mutation, whereas decreased rates are associated with defects in genes whose products are necessary for spontaneous mutagenesis. In this article, we survey and discuss the mutational specificities conferred by mutator and antimutator genes in the budding yeast Saccharomyces cerevisiae. The implications of selected aspects of the data are considered with respect to the mechanisms of spontaneous mutagenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.