ArticleJournal of virology1998
Interaction of poliovirus with its purified receptor and conformational alteration in the virion.
Article in Journal of virology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 70 citations in OpenAlex.
- The uncoating of EV71 in mature late endosomes requires CD-M6PR.Biology open · 2022Article
- Conserved Surface Residues on the Feline Calicivirus Capsid Are Essential for Interaction with Its Receptor Feline Junctional Adhesion Molecule A (fJAM-A).Journal of virology · 2018Article
- Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71.Protein & cell · 2014Article
- Human enterovirus 71 uncoating captured at atomic resolution.Journal of virology · 2014Article
- Bacterial lipopolysaccharide binding enhances virion stability and promotes environmental fitness of an enteric virus.Cell host & microbe · 2014Article
- Functional comparison of SCARB2 and PSGL1 as receptors for enterovirus 71.Journal of virology · 2013Article
- Structural analysis of coxsackievirus A7 reveals conformational changes associated with uncoating.Journal of virology · 2012Article
- Particle agglutination method for poliovirus identification.Journal of visualized experiments : JoVE · 2011Article
- Determinants of strain-specific differences in efficiency of reovirus entry.Journal of virology · 2010Article
- Interaction of alphaVbeta3 and alphaVbeta6 integrins with human parechovirus 1.Journal of virology · 2010Article
- Development of a particle agglutination method with soluble virus receptor for identification of poliovirus.Journal of clinical microbiology · 2010Article
- Expanding knowledge of P3 proteins in the poliovirus lifecycle.Future microbiology · 2010Review
- Dissecting the functional domains of a nonenveloped virus membrane penetration peptide.Journal of virology · 2009Article
- Receptor-dependent and -independent axonal retrograde transport of poliovirus in motor neurons.Journal of virology · 2009Article
- Cooperative effect of the attenuation determinants derived from poliovirus sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection model.Journal of virology · 2008Article
- Molecular aspects of poliovirus pathogenesis.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2007Review
- Early events in integrin alphavbeta6-mediated cell entry of foot-and-mouth disease virus.Journal of virology · 2005Article
- Enhanced cellular receptor usage by a bioselected variant of coxsackievirus a21.Journal of virology · 2004Article
- Interactions of foot-and-mouth disease virus with soluble bovine alphaVbeta3 and alphaVbeta6 integrins.Journal of virology · 2004Article
- Tissue-specific replicating capacity of a chimeric poliovirus that carries the internal ribosome entry site of hepatitis C virus in a new mouse model transgenic for the human poliovirus receptor.Journal of virology · 2003Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polypeptides of amino acids 1 to 241 (PVR241) and 1 to 330 (PVR330) of the human poliovirus receptor (hPVR) were produced in a baculovirus expression system. PVR241 contained extracellular domains 1 and 2 of hPVR, and PVR330 contained extracellular domains 1, 2, and 3. These peptides were purified by immunoaffinity column chromatography with an anti-hPVR monoclonal antibody (MAb). After the purification, PVR241 and PVR330 appeared to retain their native conformation as judged by reactivity with an anti-PVR MAb that recognized domain 1 of hPVR in a conformation-dependent manner. The virulent Mahoney strain of poliovirus type 1 was mixed with the purified PVRs in various concentrations. An average of at least 43 PVR330 molecules were able to bind to one virion particle under the conditions used. The equilibrium dissociation constant between the PVR330 molecule and the PVR binding site (canyon) on the virion was determined to be 4.50 +/- (0.86) x 10(-8) M at 4 degrees C. Higher rates of conformational change of the virus (160S) to 135S and 80S particles were observed as the concentration of PVR330 was increased. In this in vitro system, the ratio of the amount of the 135S particle to that of the 80S particle seemed to be always constant. After the disappearance of the 160S particle, the amount of the 80S particle was not increased by further incubation at 37 degrees C. These results suggested that the 80S particle was not derived from the 135S particle under the conditions used in this study.
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