ArticleBMJ (Clinical research ed.)1998
Identifying asthma and chronic obstructive pulmonary disease in patients with persistent cough presenting to general practitioners: descriptive study.
Article in BMJ (Clinical research ed.), 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Guideline
- Identifying Existing Evidence to Potentially Develop a Machine Learning Diagnostic Algorithm for Cough in Primary Care Settings: Scoping Review.Journal of medical Internet research · 2023Article
- Review
- Equine asthma: Integrative biologic relevance of a recently proposed nomenclature.Journal of veterinary internal medicine · 2018Review
- Article
- Trigger factors in asthma and chronic obstructive pulmonary disease: a single-centre cross-sectional survey.Singapore medical journal · 2016Article
- Influence of lung function on course of disease and response to antibiotic therapy in adult primary care patients with acute cough: a post hoc analysis of patients enrolled in a prospective multicentre study.NPJ primary care respiratory medicine · 2014Observational
- Therapeutic-diagnostic Evaluation of Chronic Cough Amongst Adults: Causes, Symptoms and Management at the Primary Care Level, Malaysia.Journal of family medicine and primary care · 2014Article
- Accuracy of symptoms, signs, and C-reactive protein for early chronic obstructive pulmonary disease.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012Article
- Undetected chronic obstructive pulmonary disease and asthma in people over 50 years with persistent cough.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010Article
- Diagnostic accuracy of spirometry in primary care.BMC pulmonary medicine · 2009Article
- Development of a questionnaire weighted scoring system to target diagnostic examinations for asthma in adults: a modelling study.BMC family practice · 2004Article
- Exploring patient- and doctor-related variables associated with antibiotic prescribing for respiratory infections in primary care.European journal of clinical pharmacology · 2003Article
- Detecting patients at a high risk of developing chronic obstructive pulmonary disease in general practice: cross sectional case finding study.BMJ (Clinical research ed.) · 2002Article
- Acute upper airway infections.British medical bulletin · 2002Review
- Prevalence of untreated asthma in a population sample of 6000 older adults in Bristol, UK.Thorax · 2001Article
- Changing the culture?The British journal of general practice : the journal of the Royal College of General Practitioners · 2001Article
- Do hospital physicians have a role in reducing antibiotic prescribing in the community?Thorax · 2000Article
- Article
- Identifying asthma and chronic obstructive pulmonary disease in patients with persistent cough. Why was no control group studied?BMJ (Clinical research ed.) · 1998Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo determine the prevalence of asthma and chronic obstructive pulmonary disease in patients not known to have these disorders, who present in general practice with persistent cough, and to ascertain criteria to help general practitioners in diagnosis.
designDescriptive study.
settingPrimary healthcare centre in the Netherlands. SUBJECTS: 192 patients aged 18-75 years, not known to have asthma or chronic obstructive pulmonary disease, attending their general practitioner with cough persisting for at least 2 weeks. : A diagnosis of asthma or chronic obstructive pulmonary disease was based on the recurrence of airway symptoms in the past year accompanied by spirometric measurements (including bronchodilator testing) and methacholine provocation tests. A scoring formula to estimate the probability of asthma or chronic obstructive pulmonary disease, based on history and physical examination, was generated by means of logistic regression.
results74 patients (39%) were classified as having asthma, 14 (7%) as having chronic obstructive pulmonary disease. The best formula for predicting asthma or chronic obstructive pulmonary disease used scores for three symptoms: (reported) wheeze, (reported) dyspnoea, and allergen induced symptoms, together with prolonged expiration, pack years of smoking, and female sex. Variables were scored 1 when present and 0 when absent, except for allergen induced symptoms (1.5) and number of pack years of smoking (n/25). With a cut off value of 3 on the scoring formula, 76% of the patients could be classified correctly.
conclusionsAbout half of patients with persistent cough who present to a general practitioner have asthma or chronic obstructive pulmonary disease. With a simple formula based on three symptoms and prolonged expiration, pack years of smoking, and female sex, most patients may be identified correctly in general practice.
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