ArticleThe Journal of urology1998
In vitro functional properties of the rat bladder regenerated by the bladder acellular matrix graft.
Article in The Journal of urology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 167 citations in OpenAlex.
- Urinary Bladder Patch Made with Decellularized Vein Scaffold Seeded with Adipose-Derived Mesenchymal Stem Cells: Model in Rabbits.Biomedicines · 2022Article
- [Advance in functional bladder engineering].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020Review
- Characterization, recellularization, and transplantation of rat decellularized testis scaffold with bone marrow-derived mesenchymal stem cells.Stem cell research & therapy · 2018Article
- Purinergic signalling in the urinary tract in health and disease.Purinergic signalling · 2014Review
- The evolution of bladder augmentation: from creating a reservoir to reconstituting an organ.Frontiers in pediatrics · 2014Review
- Tissue engineering of urinary bladder and urethra: advances from bench to patients.TheScientificWorldJournal · 2013Review
- Coadministration of platelet-derived growth factor-BB and vascular endothelial growth factor with bladder acellular matrix enhances smooth muscle regeneration and vascularization for bladder augmentation in a rabbit model.Tissue engineering. Part A · 2013Article
- Tissue engineering of urinary bladder - current state of art and future perspectives.Central European journal of urology · 2013Review
- Regenerative medicine as applied to general surgery.Annals of surgery · 2012Review
- Regenerative medicine strategies for treating neurogenic bladder.International neurourology journal · 2011Article
- Tissue engineering: current strategies and future directions.Chonnam medical journal · 2011Article
- Tissue engineering of the penis.TheScientificWorldJournal · 2011Review
- Regenerative medicine strategies for treatment of neurogenic bladder.Therapy (London, England : 2004) · 2009Article
- Functional improvement in spinal cord injury-induced neurogenic bladder by bladder augmentation using bladder acellular matrix graft in the rat.World journal of urology · 2007Article
- Regeneration of the esophagus using gastric acellular matrix: an experimental study in a rat model.Pediatric surgery international · 2007Article
- Collagen I:III ratio in canine heterologous bladder acellular matrix grafts.World journal of urology · 2006Article
- [Acellular matrix for functional reconstruction of the urogenital tract. Special form of "tissue engineering"?].Der Urologe. Ausg. A · 2004Review
- Cystometric analysis of the transplanted bladder.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Acellular human glans extracellular matrix as a scaffold for tissue engineering: in vitro cell support and biocompatibility.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Whyever bladder tissue engineering clinical applications still remain unusual even though many intriguing technological advances have been reached?Il Giornale di chirurgiaReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo assess the response of rat urinary bladder regenerated by the homologous bladder acellular matrix graft (BAMG) to in vitro electrical and pharmacologic stimuli. MATERIALS AND
methodsIn Sprague-Dawley rats, partial cystectomy (>50%) was performed, followed by BAMG augmentation cystoplasty. After 4 months, organ bath studies of tissue strips in 10 were used to compare the contractility of the BAMG regenerates and the corresponding host detrusor smooth muscle.
resultsThe BAMG regenerates exhibited contractile activity to electrical field stimulation and a qualitatively identical pattern of response to muscarinic, purinergic, alpha- and beta-adrenergic drug administration and nitric oxide. At 4 months after surgery, the maximum forces of contraction of the BAMG regenerates to carbachol stimulation amounted to close to 80% of the host bladder response. With electrical field stimulation, they equaled 44% and 62% of the host bladder response after 2.5 and 4 months, respectively. Histological and immunohistochemical studies confirmed the presence of receptors for neurotransmitters that these functional in vitro studies implied.
conclusionsThe present study provides further evidence that augmentation cystoplasty with the BAMG leads to functional regeneration of the rat bladder detrusor smooth muscle.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.