ReviewMolecular and cellular biochemistry1998
Fatty acid-binding proteins in the heart.
Review in Molecular and cellular biochemistry, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 85 citations in OpenAlex.
- Evaluation of circulating insulin-like growth factor-1, heart-type fatty acid-binding protein, and endotrophin levels as prognostic markers of COVID-19 infection severity.Virology journal · 2023Article
- Article
- Heart-type fatty acid-binding protein: an overlooked cardiac biomarker.Annals of medicine · 2020Review
- Combined assessment of myocardial damage and electrical disturbance in chronic heart failure.World journal of cardiology · 2017Article
- Serum myeloperoxidase level is associated with heart-type fatty acid-binding protein but not troponin T in patients with chronic heart failure.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2015Article
- Serum H-FABP levels in patients with hypothyroidism.Wiener klinische Wochenschrift · 2014Article
- Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity.PLoS genetics · 2014Article
- New and emerging biomarkers in left ventricular systolic dysfunction--insight into dilated cardiomyopathy.Journal of cardiovascular translational research · 2013Review
- High sensitive troponin T and heart fatty acid binding protein: novel biomarker in heart failure with normal ejection fraction? A cross-sectional study.BMC cardiovascular disorders · 2011Article
- Biomarkers in heart failure: a clinical review.Heart failure reviews · 2010Review
- Diagnostic accuracy of cardiac markers for myocardial damage after radiofrequency catheter ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2006Article
- Heart-type fatty acid binding protein is a novel prognostic marker in patients with non-ischaemic dilated cardiomyopathy.Heart (British Cardiac Society) · 2006Article
- Biochemical markers of myocyte injury in heart failure.Heart (British Cardiac Society) · 2004Review
- Utilization of triacylglycerol-rich lipoproteins by the working rat heart: routes of uptake and metabolic fates.The Journal of physiology · 2004Article
- Article
- Induction of cardiac FABP gene expression by long chain fatty acids in cultured rat muscle cells.Molecular and cellular biochemistry · 2001Article
- Review
- Involvement of membrane-associated proteins in the acute regulation of cellular fatty acid uptake.Journal of molecular neuroscience : MNReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Long-chain fatty acids are important fuel molecules for the heart, their oxidation in mitochondria providing the bulk of energy required for cardiac functioning. The low solubility of fatty acids in aqueous solutions impairs their cellular transport. However, cardiac tissue contains several proteins capable of binding fatty acids non-covalently. These fatty acid-binding proteins (FABPs) are thought to facilitate both cellular uptake and intracellular transport of fatty acids. The majority of fatty acids taken up by the heart seems to pass the sarcolemma through a carrier-mediated translocation mechanism consisting of one or more membrane-associated FABPs. Intracellular transport of fatty acids towards sites of metabolic conversion is most likely accomplished by cytoplasmic FABPs. In this review, the roles of membrane-associated and cytoplasmic FABPs in cardiac fatty acid metabolism under (patho)physiological circumstances are discussed.
Indexed as
Identifiers
9546629W1518075947What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.