ArticleBiophysical journal1998
Micropipet-based pico force transducer: in depth analysis and experimental verification.
Article in Biophysical journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 65 citations in OpenAlex.
- Quantitative comparison of cell-cell detachment force in different experimental setups.The European physical journal. E, Soft matter · 2024Article
- Membrane Tubulation with a Biomembrane Force Probe.Membranes · 2023Article
- Biomembrane force probe (BFP): Design, advancements, and recent applications to live-cell mechanobiology.Exploration (Beijing, China) · 2023Review
- A biophysical perspective on receptor-mediated virus entry with a focus on HIV.Biochimica et biophysica acta. Biomembranes · 2020Review
- Benchmarks of Biomembrane Force Probe Spring Constant Models.Biophysical journal · 2017Article
- Micropipette force probe to quantify single-cell force generation: application to T-cell activation.Molecular biology of the cell · 2017Article
- BFPTool: a software tool for analysis of Biomembrane Force Probe experiments.BMC biophysics · 2017Article
- Cell mechanics in biomedical cavitation.Interface focus · 2015Review
- Two barriers or not? Dynamic force spectroscopy on the integrin α7β1 invasin complex.Biophysical journal · 2013Article
- Effect of loading conditions on the dissociation behaviour of catch bond clusters.Journal of the Royal Society, Interface · 2012Article
- Force generation upon T cell receptor engagement.PloS one · 2011Article
- Forcing a connection: impacts of single-molecule force spectroscopy on in vivo tension sensing.Biopolymers · 2011Review
- Biomembrane force probe investigation of RNA dissociation.European biophysics journal : EBJ · 2011Article
- Squeezing and detachment of living cells.Biophysical journal · 2010Article
- Adhesion and membrane tension of single vesicles and living cells using a micropipette-based technique.The European physical journal. E, Soft matter · 2009Article
- Force versus axial deflection of pipette-aspirated closed membranes.Biophysical journal · 2007Article
- Measuring single-bond rupture forces using high electric fields in microfluidic channels and DNA oligomers as force tags.Biophysical journal · 2005Article
- Nano- to microscale dynamics of P-selectin detachment from leukocyte interfaces. II. Tether flow terminated by P-selectin dissociation from PSGL-1.Biophysical journal · 2005Article
- Nano- to microscale dynamics of P-selectin detachment from leukocyte interfaces. I. Membrane separation from the cytoskeleton.Biophysical journal · 2005Article
- Enforced detachment of red blood cells adhering to surfaces: statics and dynamics.Biophysical journal · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measurements of forces in the piconewton range are very important for the study of molecular adhesion and mechanics. Recently, a micropipet-based force transducer for this type of experiment was presented (E. Evans, K. Ritchie, and R. Merkel, 1995, Biophys. J., 68:2580-2587). In the present article we give a detailed mechanical analysis of this transducer, including nonlinear effects. An analytical expression for the transducer stiffness at small elongations is given. Using magnetic tweezers (F. Ziemann, J. Rädler, and E. Sackmann, 1994, Biophys. J., 66:2210-2216), we were able to determine the force displacement relation of this transducer experimentally. Forces from approximately 10 pN to 500 pN were applied. Theoretical predictions and experimental results coincide remarkably well.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.