Evidence map›Paper›PMID 9529893›Full record

ReviewMicrobiology and molecular biology reviews : MMBR1998

Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole.

N J Bryant, T H Stevens

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 280 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Characterization of Aspartic Proteases fromJournal of fungi (Basel, Switzerland) · 2023
    Article
  8. Potential of the Signal Peptide Derived from theApplied and environmental microbiology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. The Role of Secretory Pathways inJournal of fungi (Basel, Switzerland) · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

N J BryantInstitute of Molecular Biology, University of Oregon, Eugene 97403-1229, USA.
T H Stevens
University of Oregon · US

Funding

SORTING AND TRANSPORT OF YEAST MEMBRANE PROTEINSR01GM038006 · NIGMS · UNIVERSITY OF OREGON · PI STEVENS, TOM HALL · 1987 to 2016
$4.9M
Cell Biological Study of Eukaryotic Organelle AssemblyR37GM032448 · NIGMS · UNIVERSITY OF OREGON · PI STEVENS, TOM HALL · 2003 to 2012
$3.6M
CELL BIOLOGICAL STUDY OF EUKARYOTIC ORGANELLE ASSEMBLYR01GM032448 · NIGMS · UNIVERSITY OF OREGON · PI STEVENS, TOM HALL · 1985 to 2002
$970k
NIGMS NIH HHS GM32448NIGMS NIH HHS R01 GM032448NIGMS NIH HHS R01 GM038006NIGMS NIH HHS R37 GM032448
6 · The paper itself

Abstract

Delivery of proteins to the vacuole of the yeast Saccharomyces cerevisiae provides an excellent model system in which to study vacuole and lysosome biogenesis and membrane traffic. This organelle receives proteins from a number of different routes, including proteins sorted away from the secretory pathway at the Golgi apparatus and endocytic traffic arising from the plasma membrane. Genetic analysis has revealed at least 60 genes involved in vacuolar protein sorting, numerous components of a novel cytoplasm-to-vacuole transport pathway, and a large number of proteins required for autophagy. Cell biological and biochemical studies have provided important molecular insights into the various protein delivery pathways to the yeast vacuole. This review describes the various pathways to the vacuole and illustrates how they are related to one another in the vacuolar network of S. cerevisiae.

Indexed as

Biological TransportEndocytosisSaccharomyces cerevisiaeVacuoles

Identifiers

PMID9529893
PMCPMC98912
OpenAlexW2170298918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.