Evidence map›Paper›PMID 9525687›Full record

ArticleJournal of virology1998

Induction of mucosal B-cell memory by intramuscular inoculation of mice with rotavirus.

S E Coffin, P A Offit

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Vaccination strategies for mucosal immune responses.Clinical microbiology reviews · 2001
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

S E CoffinDivision of Immunologic and Infectious Diseases, The Children's Hospital of Philadelphia, and The University of Pennsylvania School of Medicine, 19104, USA. coffin@email.chop.edu
P A Offit
Children's Hospital of Philadelphia · USThe Wistar Institute · US

Funding

PROTECTION FROM VIRAL GASTROENTERITIS BY INTESTINAL CTLSR01AI026251 · NIAID · CHILDRENS HOSPITAL OF PHILADELPHIA · PI OFFIT, PAUL A. · 1990 to 2005
$2.0M
INDUCTION OF MUCOSAL IMMUNITY BY PARENTERAL INOCULATIONK08AI001367 · NIAID · CHILDREN'S HOSPITAL OF PHILADELPHIA · PI COFFIN, SUSAN E · 1996 to 2000
$126k
NIAID NIH HHS 1 K08 AI01367NIAID NIH HHS 1 R01 AI26251NIAID NIH HHS R01 AI026251
6 · The paper itself

Abstract

We investigated the capacity of intramuscular (i.m.) immunization with heterologous-host rotavirus (simian strain RRV) to induce mucosal virus-specific memory B cells in mice. We found that prior i.m. immunization enhanced the magnitude of mucosal virus-specific immunoglobulin A (IgA) production but did not alter the site and timing of induction of virus-specific IgA responses after challenge.

Indexed as

AnimalsAntibodies, ViralB-LymphocytesFemaleHaplorhiniImmunity, MucosalImmunoglobulin AImmunologic MemoryInjections, IntramuscularIntestinal MucosaMiceMice, Inbred BALB CRotavirusRotavirus InfectionsAntibodies, ViralImmunoglobulin A

Identifiers

PMID9525687
PMCPMC109862
OpenAlexW2150863194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.