ArticleThe Journal of physiology1998
Barium triggers rapid endocytosis in calf adrenal chromaffin cells.
Article in The Journal of physiology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Increases in intracellular pH facilitate endocytosis and decrease availability of voltage-gated proton channels in osteoclasts and microglia.The Journal of physiology · 2013Article
- Regulation by L-type calcium channels of endocytosis: an overview.Journal of molecular neuroscience : MN · 2012Review
- Rapid endocytosis and vesicle recycling in neuroendocrine cells.Cellular and molecular neurobiology · 2010Review
- Ca(2+) and calmodulin initiate all forms of endocytosis during depolarization at a nerve terminal.Nature neuroscience · 2009Article
- Low frequency stimulation of mouse adrenal slices reveals a clathrin-independent, protein kinase C-mediated endocytic mechanism.The Journal of physiology · 2003Article
- Physiological stimuli evoke two forms of endocytosis in bovine chromaffin cells.The Journal of physiology · 2001Article
- The actions of barium and strontium on exocytosis and endocytosis in the synaptic terminal of goldfish bipolar cells.The Journal of physiology · 2001Article
- Ion selectivities of the Ca(2+) sensors for exocytosis in rat phaeochromocytoma cells.The Journal of physiology · 2001Article
- Endocytosis in identified rat corticotrophs.The Journal of physiology · 2001Article
- Sustained stimulation of exocytosis triggers continuous membrane retrieval in rat pituitary somatotrophs.The Journal of physiology · 2001Article
- Synaptic vesicle endocytosis: calcium works overtime in the nerve terminal.Molecular neurobiologyReview
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
1. Changes in cell capacitance were monitored in whole-cell patch-clamp recordings from calf adrenal chromaffin cells using a software-based phase-tracking technique. Rapid endocytosis and exocytosis were observed in extracellular solutions containing either Ca2+ or Ba2+. 2. There was no significant difference in the magnitude or the time course of rapid endocytosis of cells stimulated in Ca2+ as compared to Ba2+. When cells were pretreated with caffeine and thapsigargin in order to deplete intracellular Ca2+ stores, rapid endocytosis in Ba2+ was not affected. This indicates that Ba2+ itself is capable of supporting rapid endocytosis. 3. The application of the calmodulin inhibitor calmidazolium via the intracellular pipette solution did not inhibit rapid endocytosis. Although our findings are inconsistent with an immediate requirement for calmodulin in rapid endocytosis, they do not rule out an involvement on a longer time scale. 4. While rapid endocytosis was not affected by the substitution of Ca2+ with Ba2+, the maximum rate of exocytosis was higher in cells stimulated in Ca2+ than in Ba2+. Since Ba2+ currents were much larger than Ca2+ currents during depolarizations to +10 mV (the test potential used in these experiments), Ba2+ appears to be less efficient at promoting exocytosis than Ca2+.
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Registered trials
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