ArticleJournal of clinical microbiology1998
Species-specific and ubiquitous-DNA-based assays for rapid identification of Staphylococcus aureus.
Article in Journal of clinical microbiology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
127 citing papers in PubMed, 492 citations in OpenAlex.
- Co-detection of antimicrobial resistance and virulence-associated determinants in Staphylococcus aureus isolated from radicular cysts in a post-disaster region of Türkiye.BMC oral health · 2026Article
- Phylogenetic Footprints of Coagulase-Negative Staphylococci and Mammaliicoccus Isolated From Raw Caprine Milk.MicrobiologyOpen · 2025Article
- Jerky and Biltong from the Czech Retail Market: Microbial Quality, Chemical Composition, and Other Quality Characteristics.Foods (Basel, Switzerland) · 2025Article
- Prevalence and molecular characterization of methicillin-resistant Staphylococcus aureus (MRSA) in acute and chronic sinusitis.Molecular biology reports · 2025Article
- Molecular Differentiation and Detection of AMR Genes from NosocomialPathogens (Basel, Switzerland) · 2025Article
- Asymptomatic carriage and molecular characterization of Staphylococcus aureus in pre-clinical and clinical medical students.Folia microbiologica · 2025Article
- Insight into antistaphylococcal effect of chlorinated 1-hydroxynaphthalene-2-carboxanilides.ADMET & DMPK · 2025Article
- Surveillance of public health pathogens in Lagos wastewater canals: a cross-sectional study.BMC public health · 2024Article
- In Vitro Susceptibility of Clinical and Carrier Strains ofInternational journal of molecular sciences · 2024Article
- Sub-inhibitory concentrations of ceftriaxone induce morphological alterations and PIA-independent biofilm formation in Staphylococcus aureus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Novel helix loop-mediated isothermal amplification (HAMP) assay for colorimetric detection of Staphylococcus aureus in milk.World journal of microbiology & biotechnology · 2023Article
- A Study on the Epidemiological-Molecular Role ofAntibiotics (Basel, Switzerland) · 2023Article
- Resistance profile and biofilm production capacity of Staphylococcus spp. beef slaughterhouse isolates and their sensitivity to Rosmarinus officinalis essential oil.Veterinary research communications · 2023Article
- Resistance Profile of Bovine Mastitis Isolates, Presence of theAnimals : an open access journal from MDPI · 2023Article
- A pseudo-outbreak of MRSA due to laboratory contamination related to MRSA carriage of a laboratory staff member.Antimicrobial resistance and infection control · 2023Article
- Livestock, pets and humans as carriers of methicillin-resistantVeterinary research forum : an international quarterly journal · 2023Article
- First Evidence of the Presence of the Causative Agent of Caseous Lymphadenitis-Pathogens (Basel, Switzerland) · 2022Article
- IG1, a Mansonone F Analog, Exhibits Antibacterial Activity againstLife (Basel, Switzerland) · 2022Article
- High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria.Antimicrobial resistance and infection control · 2022Article
- Molecular Epidemiology ofAntibiotics (Basel, Switzerland) · 2022Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Staphylococcus aureus is the cause of serious infections in humans, including endocarditis, deep-seated abscesses, and bacteremia, which lead to toxic and septic shock syndromes. Rapid and direct identification of this bacterium specifically and ubiquitously directly from clinical specimens would be useful in improving the diagnosis of S. aureus infections in the clinical microbiology laboratory. A wide variety of kits based on biochemical characteristics efficiently identify S. aureus, but the rapidity and the accuracy of each of these methods combined with testing of clinically relevant antibiotic resistance genes need to be improved. On the basis of hybridization assays with randomly selected clones from an S. aureus genomic library, we have identified a chromosomal DNA fragment which is specific for S. aureus and which detected all 82 S. aureus isolates tested. This 442-bp fragment was sequenced and was used to design a set of PCR amplification primers. The PCR assay was also specific and ubiquitous for the identification from bacterial cultures of 195 clinical strains of S. aureus isolated from a variety of anatomical sites and obtained from hospitals throughout the world. The PCR assay that we have developed is simple and can be performed in about 1 h. This DNA-based test provides a novel diagnostic tool for the diagnosis of S. aureus infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.