ArticleGenetics1998
Analysis of temperature-sensitive mutants reveals new genes involved in the courtship song of Drosophila.
Article in Genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 104 citations in OpenAlex.
- On the integrative taxonomy of Trichophoromyia Barretto, 1962 and its relationship with Nyssomyia Barretto, 1962 (Diptera, Psychodidae, Phlebotominae): species delimitation, phylogeny, genus and subgenus description.Parasites & vectors · 2025Article
- Direct and transgenerational effects of tetracyclines on the microbiome, transcriptome, and male mating behavior of the sheep blowfly Lucilia cuprina.G3 (Bethesda, Md.) · 2025Article
- Molecular correlates of swarming behaviour inBiology letters · 2024Article
- Inbreeding-Driven Innate Behavioral Changes inBiology · 2023Article
- The gut-microbiota-brain axis in autism: what Drosophila models can offer?Journal of neurodevelopmental disorders · 2021Review
- Article
- The genetic basis of diurnal preference in Drosophila melanogaster.BMC genomics · 2020Article
- Behavioral Evolution ofGenes · 2020Review
- Evolution of Reproductive Behavior.Genetics · 2020Review
- Article
- FemaleBiology open · 2018Article
- The Role of Transposable Elements in Speciation.Genes · 2018Review
- Regulation of gene expression and RNA editing in Drosophila adapting to divergent microclimates.Nature communications · 2017Article
- Paternal diet affects differential gene expression, but not sperm competition, in sons.Biology letters · 2017Article
- Article
- Genome-wide screen for modifiers of Na (+) /K (+) ATPase alleles identifies critical genetic loci.Molecular brain · 2014Article
- No boundaries: genomes, organisms, and ecological interactions responsible for divergence and reproductive isolation.The Journal of heredity · 2014Review
- Larval ethanol exposure alters free-running circadian rhythm and per Locus transcription in adult D. melanogaster period mutants.Behavioural brain research · 2013Article
- When population and evolutionary genetics met behaviour.Memorias do Instituto Oswaldo Cruz · 2013Review
- Two distinct genomic regions, harbouring the period and fruitless genes, affect male courtship song in Drosophila montana.Heredity · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
cacophony (cac), a mutation affecting the courtship song in Drosophila melanogaster, is revealed to cause temperature-sensitive (TS) abnormalities. When exposed to high temperatures (37 degrees), cac flies show frequent convulsions and pronounced locomotor defects. This TS phenotype seems consistent with the idea that cac is a mutation in a calcium-channel gene; it maps to the same X-chromosomal locus that encodes the polypeptide comprising the alpha-1 subunit of this membrane protein. Analysis of the courtship song of some TS physiological mutants showed that slowpoke mutations, which affect a calcium-activated potassium channel, cause severe song abnormalities. Certain additional TS mutants, in particular para(ts1) and nap(ts1), exhibit subtler song defects. The results therefore suggest that genes involved in ion-channel function are a potential source of intraspecific genetic variation for song parameters, such as the number of cycles present in "pulses" of tone or the rate at which pulses are produced by the male's courtship wing vibrations. The implications of these findings from the perspective of interspecific lovesong variations in Drosophila are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.