Evidence map›Paper›PMID 9503260›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)1997

Hormonal influences on brain ageing quality: focus on corticotropin releasing hormone-, vasopressin- and oxytocin-immunoreactive neurones in the human brain.

L Calzà, M Pozza, F Coraddu, G Farci, L Giardino

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Oxytocin attenuates neural response to emotional faces in social drinkers: an fMRI study.European archives of psychiatry and clinical neuroscience · 2021
    Trial
  2. Article
  3. Oxytocin and women's health in midlife.The Journal of endocrinology · 2024
    Review
  4. Oxytocin Levels in Children with Separation Anxiety and Their Mothers before and after Treatment.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023
    Article
  5. Article
  6. Review
  7. Observational
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

L CalzàInstitute of Human Physiology, University of Cagliari, Italy.
M Pozza
F Coraddu
G Farci
L Giardino
Hesperia Hospital · ITUniversity of Cagliari · ITAzienda Ospedaliera G. Brotzu · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper we have investigated the distribution of corticotropin releasing hormone (CRH)-, vasopressin- and oxytocin-immunoreactive (IR) neurones in the paraventricular nucleus in the senile compared to the adult human brain. We found a higher number of CRH-IR neurones in senile compared to adult subjects. Vasopressin- and oxytocin-IR neurones were instead more weakly stained in the former compared to latter. These results support a hypothalamic involvement in promoting the higher activity of the hypothalamus-pituitary-adrenal axis and, thus, higher glucocorticoid plasma levels which have been described in the elderly.

Indexed as

AgedAgingBrainBrain ChemistryCorticotropin-Releasing HormoneFemaleGlucocorticoidsHormonesHumansMaleMiddle AgedNerve DegenerationNeuronsOxytocinParaventricular Hypothalamic NucleusRisk FactorsCorticotropin-Releasing HormoneGlucocorticoidsHormonesOxytocinThyroid HormonesVasopressins

Identifiers

PMID9503260
OpenAlexW2045781282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.