ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1998
Honeybee blue- and ultraviolet-sensitive opsins: cloning, heterologous expression in Drosophila, and physiological characterization.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 94 citations in OpenAlex.
- A comprehensive characterization of opsin distribution across the visual system in the three castes of the honeybee.iScience · 2025Article
- Opsin gene expression plasticity and spectral sensitivity in male damselflies could mediate female colour morph detection.Proceedings. Biological sciences · 2025Article
- Genome-Wide Association Study and transcriptome analysis reveals a complex gene network that regulates opsin gene expression and cell fate determination inbioRxiv : the preprint server for biology · 2024Article
- Molecular Evolution of Malacostracan Short Wavelength Sensitive Opsins.Journal of molecular evolution · 2023Article
- Jewel Beetle Opsin Duplication and Divergence Is the Mechanism for Diverse Spectral Sensitivities.Molecular biology and evolution · 2023Article
- Molecular advances to study the function, evolution and spectral tuning of arthropod visual opsins.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Evolutionary history limits species' ability to match colour sensitivity to available habitat light.Proceedings. Biological sciences · 2022Article
- Rhodopsins: An Excitingly Versatile Protein Species for Research, Development and Creative Engineering.Frontiers in chemistry · 2022Review
- Organ-specific transcriptome analysis reveals differential gene expression in different castes under natural conditions in Apis cerana.Scientific reports · 2021Article
- Opsin expression patterns coincide with photoreceptor development during pupal development in the honey bee, Apis mellifera.BMC developmental biology · 2018Article
- A ciliary opsin in the brain of a marine annelid zooplankton is ultraviolet-sensitive, and the sensitivity is tuned by a single amino acid residue.The Journal of biological chemistry · 2017Article
- Drosophila Rhodopsin 7 can partially replace the structural role of Rhodopsin 1, but not its physiological function.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017Article
- Overcoming the loss of blue sensitivity through opsin duplication in the largest animal group, beetles.Scientific reports · 2017Article
- Unique Temporal Expression of Triplicated Long-Wavelength Opsins in Developing Butterfly Eyes.Frontiers in neural circuits · 2017Article
- Rhodopsin coexpression in UV photoreceptors of Aedes aegypti and Anopheles gambiae mosquitoes.The Journal of experimental biology · 2014Article
- Both the anterior and posterior eyes function as photoreceptors for photoperiodic termination of diapause in the two-spotted spider mite.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
- Genetic basis of triatomine behavior: lessons from available insect genomes.Memorias do Instituto Oswaldo Cruz · 2013Review
- Dynamin- and Rab5-dependent endocytosis is required to prevent Drosophila photoreceptor degeneration.Journal of cell science · 2011Article
- Article
- Molecular evidence for color discrimination in the Atlantic sand fiddler crab, Uca pugilator.The Journal of experimental biology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The honeybee (Apis mellifera) visual system contains three classes of retinal photoreceptor cells that are maximally sensitive to light at 440 nm (blue), 350 nm (ultraviolet), and 540 nm (green). We performed a PCR-based screen to identify the genes encoding the Apis blue- and ultraviolet (UV)-sensitive opsins. We obtained cDNAs that encode proteins having a high degree of sequence and structural similarity to other invertebrate and vertebrate visual pigments. The Apis blue opsin cDNA encodes a protein of 377 amino acids that is most closely related to other invertebrate visual pigments that are thought to be blue-sensitive. The UV opsin cDNA encodes a protein of 371 amino acids that is most closely related to the UV-sensitive Drosophila Rh3 and Rh4 opsins. To test whether these novel Apis opsin genes encode functional visual pigments and to determine their spectral properties, we expressed them in the R1-6 photoreceptor cells of blind ninaE mutant Drosophila, which lack the major opsin of the fly compound eye. We found that the expression of either the Apis blue- or UV-sensitive opsin in transgenic flies rescued the visual defect of ninaE mutants, indicating that both genes encode functional visual pigments. Spectral sensitivity measurements of these flies demonstrated that the blue and UV visual pigments are maximally sensitive to light at 439 and 353 nm, respectively. These maxima are in excellent agreement with those determined previously by single-cell recordings from Apis photoreceptor cells and provide definitive evidence that the genes described here encode visual pigments having blue and UV sensitivity.
Indexed as
Identifiers
9502802PMC6793122W1684558829What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.