ArticleProceedings of the National Academy of Sciences of the United States of America1998
Alignment enhances the cell-to-cell transfer of pilus phenotype.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Article
- Kin recognition and outer membrane exchange (OME) in myxobacteria.Current opinion in microbiology · 2020Review
- MYXO-CTERM sorting tag directs proteins to the cell surface via the type II secretion system.Molecular microbiology · 2020Article
- Agent-Based Modeling Reveals Possible Mechanisms for Observed Aggregation Cell Behaviors.Biophysical journal · 2018Article
- Self-identity reprogrammed by a single residue switch in a cell surface receptor of a social bacterium.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Exopolysaccharide microchannels direct bacterial motility and organize multicellular behavior.The ISME journal · 2016Article
- Sibling Rivalry in Myxococcus xanthus Is Mediated by Kin Recognition and a Polyploid Prophage.Journal of bacteriology · 2016Article
- How Myxobacteria Cooperate.Journal of molecular biology · 2015Review
- Mechanism for Collective Cell Alignment in Myxococcus xanthus Bacteria.PLoS computational biology · 2015Article
- Cell rejuvenation and social behaviors promoted by LPS exchange in myxobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Article
- A genetic screen in Myxococcus xanthus identifies mutants that uncouple outer membrane exchange from a downstream cellular response.Journal of bacteriology · 2014Article
- Transmission of a signal that synchronizes cell movements in swarms of Myxococcus xanthus.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Myxobacteria produce outer membrane-enclosed tubes in unstructured environments.Journal of bacteriology · 2014Article
- Molecular recognition in myxobacterial outer membrane exchange: functional, social and evolutionary implications.Molecular microbiology · 2014Review
- Molecular recognition by a polymorphic cell surface receptor governs cooperative behaviors in bacteria.PLoS genetics · 2013Article
- Identification of the cglC, cglD, cglE, and cglF genes and their role in cell contact-dependent gliding motility in Myxococcus xanthus.Journal of bacteriology · 2012Article
- Cell contact-dependent outer membrane exchange in myxobacteria: genetic determinants and mechanism.PLoS genetics · 2012Article
- Cell flexibility affects the alignment of model myxobacteria.Biophysical journal · 2010Article
- The selective value of bacterial shape.Microbiology and molecular biology reviews : MMBR · 2006Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Social gliding motility of Myxococcus xanthus requires polar type IV pili. Tgl mutants lack pili and lack social motility. However, both defects can be rescued phenotypically, but not genotypically, when tgl+ donor and tgl- recipient cells make physical contact with each other. What is the cellular and molecular basis of this transfer of phenotype, which is called stimulation? Stimulation does not occur in liquid nor in soft (0.5%) agar; however, on a more firm surface (1.0% agar) cells stimulate each other efficiently. Microscopy revealed that cells placed on 1.0% agar readily became aligned whereas they remained poorly aligned on 0.5% agar. It was observed, moreover, that stimulation is greatly reduced when donor and recipient cells lack the ability to move because of mutations in any of several different motility genes. Microscopy showed that motile cells became highly aligned, and can even align nonmotile cells. Using a stimulation assay based on the assembly of pili, a strong correlation was found between conditions that promote cell alignment and the speed or extent of stimulation. Because pili are assembled only at the end(s) of a cell, and a parallel alignment of cells in contact brings them end-to-end, we would suggest that end-to-end contacts are important for stimulation of pilus assembly.
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