ArticleThorax1997
Airway epithelial repair: breathtakingly quick and multipotentially pathogenic.
Article in Thorax, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Airways exudation of plasma macromolecules: Innate defense, epithelial regeneration, and asthma.The Journal of allergy and clinical immunology · 2019Review
- Neuropeptides SP and CGRP Diminish theMediators of inflammation · 2018Article
- Opposing effects of in vitro differentiated macrophages sub-type on epithelial wound healing.PloS one · 2017Article
- Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon.TheScientificWorldJournal · 2017Review
- Perspectives of purinergic signaling in stem cell differentiation and tissue regeneration.Purinergic signalling · 2012Review
- Understanding cellular mechanisms underlying airway epithelial repair: selecting the most appropriate animal models.TheScientificWorldJournal · 2012Review
- Pathogenesis and disease mechanisms of occupational asthma.Immunology and allergy clinics of North America · 2011Review
- Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia.American journal of respiratory and critical care medicine · 2011Article
- Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length.Respiratory research · 2010Article
- Pulmonary fibrosis: pathogenesis, etiology and regulation.Mucosal immunology · 2009Review
- Airway epithelial cells: current concepts and challenges.Proceedings of the American Thoracic Society · 2008Review
- Tissue inhibitor of metalloproteinase-1 moderates airway re-epithelialization by regulating matrilysin activity.The American journal of pathology · 2008Article
- NADPH oxidases in lung biology and pathology: host defense enzymes, and more.Free radical biology & medicine · 2008Review
- Regulation of airway mucin gene expression.Annual review of physiology · 2008Review
- Airway epithelial stem cells and the pathophysiology of chronic obstructive pulmonary disease.Proceedings of the American Thoracic Society · 2006Review
- Review
- Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium.The American journal of pathology · 2003Article
- Interaction of environmental allergens with airway epithelium as a key component of asthma.Current allergy and asthma reports · 2003Review
- Degranulation patterns of eosinophil granulocytes as determinants of eosinophil driven disease.Thorax · 2001Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.