Evidence map›Paper›PMID 9484827›Full record

ArticleBritish journal of cancer1998

Prognostic value of ERBB-1, VEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas.

M Volm, W Rittgen, P Drings

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in British journal of cancer, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 178 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Chronic and acute arsenic exposure enhance EGFR expression via distinct molecular mechanisms.Toxicology in vitro : an international journal published in association with BIBRA · 2020
    Article
  8. VEGF Signaling in Neurological Disorders.International journal of molecular sciences · 2018
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Strong expression of cyclin B2 mRNA correlates with a poor prognosis in patients with non-small cell lung cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Article
  15. Effect of chemotherapy on quality of life in patients with non-small cell lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014
    Review
  16. MicroRNA-497 and bufalin act synergistically to inhibit colorectal cancer metastasis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M VolmDepartment of Oncological Diagnostics and Therapy, German Cancer Research Center, Heidelberg.
W Rittgen
P Drings
Heidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with previously untreated squamous cell lung carcinomas were evaluated to see if combining the expression of molecular and cellular factors with the most important clinical prognostic factors could improve the diagnostic ability to predict prognosis. For this reason, immunohistochemistry was used to examine the squamous cell lung carcinomas from 121 patients for their expression of ERBB-1, vascular endothelial growth factor (VEGF), cyclin A, FOS, JUN and MYC. Median survival was shorter for patients with ERBB-1-, VEGF-, cyclin A-, FOS-, or JUN-positive tumours. For those patients with positive lymph node involvement, the survival times were also shorter in the VEGF-positive, cyclin A-positive and FOS-positive groups. Multivariate analysis independently demonstrated a significant prognostic value for lymph node involvement, VEGF and FOS.

Indexed as

AdultAgedCarcinoma, Squamous CellCyclin AEndothelial Growth FactorsErbB ReceptorsFemaleHumansLung NeoplasmsLymphokinesMaleMiddle AgedNeoplasm ProteinsPrognosisProto-Oncogene Proteins c-fosProto-Oncogene Proteins c-junCyclin AEndothelial Growth FactorsErbB ReceptorsLymphokinesNeoplasm ProteinsProto-Oncogene Proteins c-fosProto-Oncogene Proteins c-junProto-Oncogene Proteins c-mycVascular Endothelial Growth Factor AVascular Endothelial Growth Factors

Identifiers

PMID9484827
PMCPMC2149928
OpenAlexW2019995422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.