ArticlePlant molecular biology1998
The Arabidopsis AUX1 gene: a model system to study mRNA processing in plants.
Article in Plant molecular biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Up-Frameshift Factors from Phytopathogenic Fungi Play a Crucial Role in Nonsense-Mediated mRNA Decay.Journal of fungi (Basel, Switzerland) · 2025Article
- A root cap-localized NAC transcription factor controls root halotropic response to salt stress in Arabidopsis.Nature communications · 2024Article
- Fluctuating auxin response gradients determine pavement cell-shape acquisition.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Article
- Root Gravitropism Is Regulated by a Crosstalk betweenPlant physiology · 2018Article
- ArabidopsisPlant physiology · 2018Article
- Arabidopsis seed germination speed is controlled by SNL histone deacetylase-binding factor-mediated regulation of AUX1.Nature communications · 2016Article
- Parsimonious Model of Vascular Patterning Links Transverse Hormone Fluxes to Lateral Root Initiation: Auxin Leads the Way, while Cytokinin Levels Out.PLoS computational biology · 2015Article
- Root growth is modulated by differential hormonal sensitivity in neighboring cells.Genes & development · 2014Article
- The manipulation of auxin in the abscission zone cells of Arabidopsis flowers reveals that indoleacetic acid signaling is a prerequisite for organ shedding.Plant physiology · 2013Article
- High resolution melting analysis for the detection of EMS induced mutations in wheat SBEIIa genes.BMC plant biology · 2011Article
- The AUX1 LAX family of auxin influx carriers is required for the establishment of embryonic root cell organization in Arabidopsis thaliana.Annals of botany · 2010Article
- Auxin influx carriers stabilize phyllotactic patterning.Genes & development · 2008Article
- Two point mutations identified in emmer wheat generate null Wx-A1 alleles.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2005Article
- Structure-function analysis of the presumptive Arabidopsis auxin permease AUX1.The Plant cell · 2004Article
- Enhancing the anaerobic response.Annals of botany · 2003Review
- Auxin and ethylene response interactions during Arabidopsis root hair development dissected by auxin influx modulators.Plant physiology · 2002Article
- Chromosaponin I specifically interacts with AUX1 protein in regulating the gravitropic response of Arabidopsis roots.Plant physiology · 2001Article
- The rug3 locus of pea encodes plastidial phosphoglucomutase.Plant physiology · 2000Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is advantageous for an organism to be able to remove aberrant mRNAs that have either been incorrectly transcribed or processed in order to prevent the accumulation of potentially harmful proteins. The selective degradation of nonsense containing transcripts has been described in yeast. Caenorhabditis elegans and plants. The ease of identification of new mutant alleles in the AUX1 gene of Arabidopsis thaliana has provided a useful system to study novel mutations affecting mRNA stability and pre-mRNA splicing. To date 50 alleles of AUX1 have been identified of which 14 have been characterised at the sequence level. Eight of the characterised alleles encode missense mutations while the others cause nonsense mutations or splicing defects. The 2 splicing mutants identified affect the 5' or 3' splice sites and lead to cryptic splicing events resulting in premature stop codons. The AUX1 mRNA levels of the nonsense containing mutants are reduced compared to the wild-type or missense mutants whereas those of a control transcript (SecY) are unaltered. This provides further evidence for a nonsense-mediated mRNA degradation mechanism in plants and provides a system to study the phenomenon further in Arabidopsis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.