ArticleProceedings of the National Academy of Sciences of the United States of America1998
A poly(A) binding protein functions in the chloroplast as a message-specific translation factor.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 113 citations in OpenAlex.
- Assembly and Repair of Photosystem II inPlants (Basel, Switzerland) · 2024Review
- An Organelle RNA Recognition Motif Protein Is Required for Photosystem II SubunitPlant physiology · 2017Article
- Activation of an Endoribonuclease by Non-intein Protein Splicing.The Journal of biological chemistry · 2016Article
- Redox regulation of thylakoid protein kinases and photosynthetic gene expression.Antioxidants & redox signaling · 2013Review
- How to build functional thylakoid membranes: from plastid transcription to protein complex assembly.Planta · 2013Review
- The effect of different 3' untranslated regions on the accumulation and stability of transcripts of a gfp transgene in chloroplasts of transplastomic tobacco.Plant molecular biology · 2011Article
- Red light and calmodulin regulate the expression of the psbA binding protein genes in Chlamydomonas reinhardtii.Plant & cell physiology · 2010Article
- Stress induces the assembly of RNA granules in the chloroplast of Chlamydomonas reinhardtii.The Journal of cell biology · 2008Article
- Article
- Transcriptional profiling of chickpea genes differentially regulated in response to high-salinity, cold and drought.BMC genomics · 2007Article
- The nuclear-encoded factor HCF173 is involved in the initiation of translation of the psbA mRNA in Arabidopsis thaliana.The Plant cell · 2007Article
- ABA-responsive RNA-binding proteins are involved in chloroplast and stromule function in Arabidopsis seedlings.Planta · 2006Article
- Derepression of the Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cells.Genes & development · 2006Article
- Presence of a poly(A) binding protein and two proteins with cell cycle-dependent phosphorylation in Crithidia fasciculata mRNA cycling sequence binding protein II.Eukaryotic cell · 2004Article
- The thioredoxin superfamily in Chlamydomonas reinhardtii.Photosynthesis research · 2004Article
- The translational apparatus of Chlamydomonas reinhardtii chloroplast.Photosynthesis research · 2004Article
- Light control of nuclear gene mRNA abundance and translation in tobacco.Plant physiology · 2003Article
- Chloroplast RNA-binding proteins.Current genetics · 2003Review
- Molecular map of the Chlamydomonas reinhardtii nuclear genome.Eukaryotic cell · 2003Article
- Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
High-affinity binding of a set of proteins with specificity for the 5' untranslated region (UTR) of the Chlamydomonas reinhardtii chloroplast psbA mRNA correlates with light-regulated translational activation of this message. We have isolated a cDNA encoding the main psbA RNA binding protein, RB47, and identified this protein as a member of the poly(A) binding protein family. Poly(A) binding proteins are a family of eukaryotic, cytoplasmic proteins thought to bind poly(A) tails of mRNAs and play a role in translational regulation. In vitro translation of RNA transcribed from the RB47 cDNA produces a precursor protein that is efficiently transported into the chloroplast and processed to the mature 47-kDa protein. RB47 expressed and purified from Escherichia coli binds to the psbA 5' UTR with similar specificity and affinity as RB47 isolated from C. reinhardtii chloroplasts. The identification of a normally cytoplasmic translation factor in the chloroplast suggests that the prokaryotic-like chloroplast translation machinery utilizes a eukaryotic-like initiation factor to regulate the translation of a key chloroplast mRNA. These data also suggest that poly(A) binding proteins may play a wider role in translation regulation than previously appreciated.
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