ArticleProceedings of the National Academy of Sciences of the United States of America1998
Reversible dissociation of coatomer: functional characterization of a beta/delta-coat protein subcomplex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 77 citations in OpenAlex.
- COPI coatomer subunit α-COP interacts with the RNA binding protein Nucleolin via a C-terminal dilysine motif.Human molecular genetics · 2023Article
- The role of CaMKK2 in Golgi-associated vesicle trafficking.Biochemical Society transactions · 2023Review
- Identification of Prognostic and Chemopredictive microRNAs for Non-Small-Cell Lung Cancer by Integrating SEER-Medicare Data.International journal of molecular sciences · 2021Article
- A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.Life science alliance · 2020Article
- δ-COP contains a helix C-terminal to its longin domain key to COPI dynamics and function.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.Molecular biology of the cell · 2013Article
- COPI budding within the Golgi stack.Cold Spring Harbor perspectives in biology · 2011Review
- Several ADP-ribosylation factor (Arf) isoforms support COPI vesicle formation.The Journal of biological chemistry · 2011Article
- Entry and exit mechanisms at the cis-face of the Golgi complex.Cold Spring Harbor perspectives in biology · 2011Review
- Article
- Reconstitution of the cell cycle-regulated Golgi disassembly and reassembly in a cell-free system.Nature protocols · 2010Article
- Following the fate in vivo of COPI vesicles generated in vitro.Traffic (Copenhagen, Denmark) · 2009Article
- Arf GAP2 is positively regulated by coatomer and cargo.Cellular signalling · 2009Article
- Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.The Journal of cell biology · 2008Article
- Membrane curvature induced by Arf1-GTP is essential for vesicle formation.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Kinetic analysis of Arf GAP1 indicates a regulatory role for coatomer.The Journal of biological chemistry · 2008Article
- Molecular mechanism of mitotic Golgi disassembly and reassembly revealed by a defined reconstitution assay.The Journal of biological chemistry · 2008Article
- Article
- Active ADP-ribosylation factor-1 (ARF1) is required for mitotic Golgi fragmentation.The Journal of biological chemistry · 2007Article
- Coatomer, the coat protein of COPI transport vesicles, discriminates endoplasmic reticulum residents from p24 proteins.Molecular and cellular biology · 2006Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
COPI-coated vesicles mediate protein transport within the early secretory pathway. Their coat consists of ADP ribosylation factor (ARF1, a small guanosine nucleotide binding protein), and coatomer, a cytosolic complex composed of seven subunits, alpha- to zeta-coat proteins (COPs). For coat formation that initiates budding of a vesicle, ARF1 is recruited to the Golgi membrane from the cytosol in its GTP-bound form, and subsequently, coatomer can bind to the membrane. To identify a minimal structure of coatomer capable to bind to Golgi membranes in an ARF1-dependent manner, we have established a procedure to dissociate coatomer under conditions that allow reassociation of the subunits to a complete and functional complex. After dissociation, subunits or subcomplexes can be isolated and may be expected to be functional. Herein we describe isolation of a subcomplex of coatomer consisting of beta- and delta-COPs that is able to bind to Golgi membranes in an ARF1- and GTP-dependent manner.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.