ArticleGenetics1998
Long, interrupted conversion tracts initiated by cog in Neurospora crassa.
Article in Genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Meiotic Recombination in Neurospora crassa Proceeds by Two Pathways with Extensive Holliday Junction Migration.PloS one · 2016Article
- Use of fluorescent protein to analyse recombination at three loci in Neurospora crassa.Fungal genetics and biology : FG & B · 2012Article
- A crossover hotspot near his-3 in Neurospora crassa is a preferential recombination termination site.Molecular genetics and genomics : MGG · 2012Article
- Genome-wide survey of post-meiotic segregation during yeast recombination.Genome biology · 2011Article
- Chromosome pairing and meiotic recombination in Neurospora crassa spo11 mutants.Current genetics · 2006Article
- MuDR transposase increases the frequency of meiotic crossovers in the vicinity of a Mu insertion in the maize a1 gene.Genetics · 2005Article
- Alleles of the hotspot cog are codominant in effect on recombination in the his-3 region of Neurospora.Genetics · 2004Article
- Recombination at his-3 in Neurospora declines exponentially with distance from the initiator, cog.Genetics · 2002Article
- Molecular characterization of meiotic recombination across the 140-kb multigenic a1-sh2 interval of maize.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Recombination events in Neurospora crassa may cross a translocation breakpoint by a template-switching mechanism.Genetics · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple polymorphisms distinguish Emerson and Lindegren strains of Neurospora crassa within the histidine-3 gene and in its distal flank. Restriction site and sequence length polymorphism in a set of 14 PCR products covering this 6.9-kb region were used to identify the parental origin of DNA sequence information in prototrophic progeny of crosses heterozygous for auxotrophic mutations in his-3 and the silent sequence differences. Forty-one percent of conversion tracts are interrupted. Where the absence of rec-2+ permits activity of the recombination hotspot cog, conversion appears to originate at cog and conversion tracts are up to 5.9 kb long. The chromosome bearing cog(L), the dominant allele that confers a high frequency of recombination, is almost invariably the recipient of information. In progeny from crosses heterozygous rec-2/rec-2+, conversion tracts are much shorter, most are not initiated at cog and either chromosome seems equally likely to be converted. Although 32% of his-3 prototrophs have a crossover that may be associated with conversion, it is suggested that the apparent association between conversion and crossing over at this locus may be due to confounding of coincidental events rather than to a mechanistic relationship.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.