ReviewJournal of clinical immunology1998
Oral tolerance.
Review in Journal of clinical immunology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis?Current rheumatology reports · 2021Review
- Staphylococcal enterotoxins in the etiopathogenesis of mucosal autoimmunity within the gastrointestinal tract.Toxins · 2014Review
- Article
- Diminution of Circulating CD4+CD25 high T cells in naïve Crohn's disease.Digestive diseases and sciences · 2009Article
- Suppression of Th1 and Th17, but not Th2, responses in a CD8(+) T cell-mediated model of oral tolerance.Mucosal immunology · 2009Article
- Plant-based oral vaccines: results of human trials.Current topics in microbiology and immunology · 2009Review
- Ovalbumin-protein sigma 1 M-cell targeting facilitates oral tolerance with reduction of antigen-specific CD4+ T cells.Gastroenterology · 2008Article
- Are we getting enough allergens?International archives of allergy and immunology · 2008Article
- Transgenic plants for animal health: plant-made vaccine antigens for animal infectious disease control.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2008Article
- Enteroendocrine cells express functional Toll-like receptors.American journal of physiology. Gastrointestinal and liver physiology · 2007Article
- Heat shock proteins induce T cell regulation of chronic inflammation.Annals of the rheumatic diseases · 2006Review
- Article
- In vivo effects of bifidobacteria and lactoferrin on gut endotoxin concentration and mucosal immunity in Balb/c mice.Digestive diseases and sciences · 2004Article
- TGF-beta1 production in inflammatory bowel disease: differing production patterns in Crohn's disease and ulcerative colitis.Clinical and experimental immunology · 2003Article
- Inflammatory bowel disease: is the intestine a Trojan horse?Science progress · 2002Review
- Bacterial translocation and immunohistochemical measurement of gut immune function.Journal of clinical pathology · 2001Article
- Peyer's patches are required for oral tolerance to proteins.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Lamina propria lymphocytes produce interferon-gamma and develop suppressor activity in response to lactoglobulin.Digestive diseases and sciences · 2001Article
- The SAMP1/Yit mouse: another step closer to modeling human inflammatory bowel disease.The Journal of clinical investigation · 2001Review
- Tolerance and bystander suppression, with involvement of CD25-positive cells, is induced in rats receiving serum from ovalbumin-fed donors.Immunology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral tolerance is the immunologic mechanism by which the mucosal immune system maintains unresponsiveness to the myriad of antigens in the mucosal environment which might otherwise induce untoward immune responses. Recent studies have shown that it is mediated by several distinct, yet interacting mechanisms including the generation of suppressive T cells producing antigen nonspecific cytokines and the induction of clonal deletion and/or anergy. In this review of oral tolerance, we discuss these mechanisms in detail and show how oral tolerance or lack thereof may explain the occurrence of mucosal inflammation. In addition, we discuss how induction of oral tolerance can be used to treat autoimmune states.
Indexed as
Identifiers
9475350What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.