Evidence map›Paper›PMID 9468652›Full record

ArticleJournal of chromatography. A1998

Quantification of carvone, cineole, perillaldehyde, perillyl alcohol and sobrerol by isocratic high-performance liquid chromatography.

L Tao, M A Pereira

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of chromatography. A, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06924697 (Effect of Glucagon-like Peptide-1), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06924697 naenrolling by invitationstarted 2025, after this paper: background citation

Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients: Study Protocol of a Randomized, Parallel -Controlled Clinical Trial

Ran2025Enrolled46Registered outcomes6Posted comparisons0ConditionsDiabetes Mellitus, Type 2, Nicotine Dependence, CigarettesArmsApplication of GLP-1RAs drugs, DPP-4i group
Open the trial in the graph
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

L TaoDepartment of Pathology, Medical College of Ohio, Toledo 43614, USA.
M A Pereira
University of Toledo Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple and rapid isocratic HPLC assay is presented for the analysis and quantification of monoterpenes, i.e., carvone, cineole, perillaldehyde, perillyl alcohol and sobrerol in the diet of laboratory animals. The monoterpenes were extracted from the diet using 90% methanol in water. The analysis for the monoterpenes was performed by HPLC using a Whatman PartiSphere C18 column with UV detection. The mobile phase was isocratic methanol-water (72:28, v/v) for carvone, cineole, perillaldehyde and perillyl alcohol and methanol-water (65:35, v/v) for sobrerol. The method was simple with good repeatability (R.S.D. = 4.2-16.1%), reproducibility (R.S.D. = 3.7-19%), and accuracy (R.S.D. = 5.5-23.3%). The detection limit of the monoterpenes extracted from the diet was 2 micrograms/g for carvone, perillaldehyde and sobrerol, 20 micrograms/g for perillyl alcohol and 100 micrograms/g for cineole. Excellent resolution was achieved between the monoterpenes and the constituents of the diet. The method demonstrated applicability to monitoring the formulation of monoterpenes in the diet of laboratory animals.

Indexed as

CyclohexanolsMonoterpenesAnimal FeedCalibrationChromatography, High Pressure LiquidCircadian RhythmCyclohexane MonoterpenesEucalyptolMentholReproducibility of ResultsSpectrophotometry, UltravioletTerpenesTime FactorscarvoneCyclohexane MonoterpenesCyclohexanolsEucalyptolMentholMonoterpenesperillaldehydeperillyl alcoholsobrerolTerpenes

Identifiers

PMID9468652
OpenAlexW2039032608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.