ArticleThe American journal of pathology1998
Cloning and molecular characterization of part of a new gene fused to HMGIC in mesenchymal tumors.
Article in The American journal of pathology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Pooled it
- Review
- Aggressive Angiomyxoma in the Scrotum: A Case Series and Literature Review.Frontiers in surgery · 2022Article
- Potential pathogenetic link between angiomyofibroblastoma and superficial myofibroblastoma in the female lower genital tract based on a novel MTG1-CYP2E1 fusion.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021Article
- Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.Nature genetics · 2012Article
- Aggressive angiomyxoma with t(12;21) and HMGA2 rearrangement: report of a case and review of the literature.Cancer genetics and cytogenetics · 2008Review
- Deregulation of HMGA2 in an aggressive angiomyxoma with t(11;12)(q23;q15).Virchows Archiv : an international journal of pathology · 2006Article
- Aggressive angiomyxoma: a clinicopathological and immunohistochemical study of 11 cases with long-term follow-up.Virchows Archiv : an international journal of pathology · 2005Article
- The HMG I proteins: dynamic roles in gene activation, development, and tumorigenesis.Immunologic research · 2001Review
- Fusion of High Mobility Group AT-hook 2 Gene (Cancer genomics & proteomicsArticle
- Recurrent Fusion of the Genes for High-mobility Group AT-hook 2 (Cancer genomics & proteomicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aberrations of the HMGIC gene, encoding an architectural transcription factor and located in the chromosomal region 12q15, are very frequent among benign mesenchymal tumors, such as lipomas, uterine leiomyomas, or pulmonary chondroid hamartomas. These HMGIC aberrations are caused by characteristic structural chromosomal aberrations, either visible by conventional cytogenetics or as cryptic abnormalities. Some of these aberrations of chromosome 12 are not specific for particular tumor entities but can occur in a variety of tumors with HMGIC abnormalities. One such example is the pericentric inversion inv(12)(p11.2q15). Starting from the ectopic sequence derived from an HMGIC fusion transcript of an aggressive angiomyxoma with such an inversion we established three PAC clones covering the breakpoint region 12p11 and cloned part of a yet unknown gene in 12p11.2, which is fused to the third exon of HMGIC. Using fluorescence in situ hybridization with these PACs we were able to show that the same region was involved by 12p11.2 aberrations in lipomas, aggressive angiomyxomas, and pulmonary chondroid hamartomas.
Indexed as
Identifiers
9466569PMC1857946W245551696What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.