ArticleProceedings of the National Academy of Sciences of the United States of America1998
Introns and intein coding sequence in the ribonucleotide reductase genes of Bacillus subtilis temperate bacteriophage SPbeta.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 67 citations in OpenAlex.
- Article
- Phage Genome Annotation: Where to Begin and End.PHAGE (New Rochelle, N.Y.) · 2021Article
- The life cycle of SPβ and related phages.Archives of virology · 2021Review
- Genomic Characterization of Cyanophage vB_AphaS-CL131 Infecting Filamentous Diazotrophic CyanobacteriumApplied and environmental microbiology · 2019Article
- Mobile self-splicing introns and inteins as environmental sensors.Current opinion in microbiology · 2017Review
- Arabidopsis chloroplast mini-ribonuclease III participates in rRNA maturation and intron recycling.The Plant cell · 2015Article
- Correction: genomic comparison of 93 Bacillus phages reveals 12 clusters, 14 singletons and remarkable diversity.BMC genomics · 2014Article
- Enigmatic distribution, evolution, and function of inteins.The Journal of biological chemistry · 2014Review
- Bacillus subtilis class Ib ribonucleotide reductase: high activity and dynamic subunit interactions.Biochemistry · 2014Article
- Romulus and Remus, two phage isolates representing a distinct clade within the Twortlikevirus genus, display suitable properties for phage therapy applications.Journal of virology · 2013Article
- A bioinformatic analysis of ribonucleotide reductase genes in phage genomes and metagenomes.BMC evolutionary biology · 2013Article
- Cargo capacity of phages and plasmids and other factors influencing horizontal transfers of prokaryote transposable elements.Mobile genetic elements · 2012Article
- Assembly of a fragmented ribonucleotide reductase by protein interaction domains derived from a mobile genetic element.Nucleic acids research · 2011Article
- Comparative genomic analysis of 60 Mycobacteriophage genomes: genome clustering, gene acquisition, and gene size.Journal of molecular biology · 2010Article
- Complete genomic sequence of bacteriophage felix o1.Viruses · 2010Article
- Phage T4 mobE promotes trans homing of the defunct homing endonuclease I-TevIII.Nucleic acids research · 2009Article
- Unconventional GIY-YIG homing endonuclease encoded in group I introns in closely related strains of the Bacillus cereus group.Nucleic acids research · 2008Article
- Cyanobacterial ribosomal RNA genes with multiple, endonuclease-encoding group I introns.BMC evolutionary biology · 2007Article
- A functional homing endonuclease in the Bacillus anthracis nrdE group I intron.Journal of bacteriology · 2007Article
- The Bacillus subtilis nrdEF genes, encoding a class Ib ribonucleotide reductase, are essential for aerobic and anaerobic growth.Applied and environmental microbiology · 2006Article
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The two putative ribonucleotide reductase subunits of the Bacillus subtilis bacteriophage SPbeta are encoded by the bnrdE and bnrdF genes that are highly similar to corresponding host paralogs, located on the opposite replication arm. In contrast to their bacterial counterparts, bnrdE and bnrdF each are interrupted by a group I intron, efficiently removed in vivo by mRNA processing. The bnrdF intron contains an ORF encoding a polypeptide similar to homing endonucleases responsible for intron mobility, whereas the bnrdE intron has no obvious trace of coding sequence. The downstream bnrdE exon harbors an intervening sequence not excised at the level of the primary transcript, which encodes an in-frame polypeptide displaying all the features of an intein. Presently, this is the only intein identified in bacteriophages. In addition, bnrdE provides an example of a group I intron and an intein coding sequence within the same gene.
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