ArticleProceedings of the National Academy of Sciences of the United States of America1998
Blood-borne seeding by hematopoietic and endothelial precursors from the allantois.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells.PLoS biology · 2025Article
- Contribution of a GATA4-Expressing Hematopoietic Progenitor Lineage to the Adult Mouse Endothelium.Cells · 2020Article
- Induction of developmental hematopoiesis mediated by transcription factors and the hematopoietic microenvironment.Annals of the New York Academy of Sciences · 2020Review
- Restricted intra-embryonic origin of bona fide hematopoietic stem cells in the chicken.Development (Cambridge, England) · 2017Article
- Article
- Article
- Contribution of the Local RAS to Hematopoietic Function: A Novel Therapeutic Target.Frontiers in endocrinology · 2013Review
- Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs.Blood · 2013Article
- Embryogenesis of the first circulating endothelial cells.PloS one · 2013Article
- Article
- Life is a pattern: vascular assembly within the embryo.Frontiers in bioscience (Elite edition) · 2012Review
- Human placenta and chorion: potential additional sources of hematopoietic stem cells for transplantation.Transfusion · 2011Article
- Extraembryonic origin of circulating endothelial cells.PloS one · 2011Article
- Placenta as a source of hematopoietic stem cells.Trends in molecular medicine · 2010Review
- Placenta as a newly identified source of hematopoietic stem cells.Current opinion in hematology · 2010Review
- Hematopoietic stem cell development in the placenta.The International journal of developmental biology · 2010Review
- The opening act: vasculogenesis and the origins of circulation.Arteriosclerosis, thrombosis, and vascular biology · 2009Review
- New morphological aspects of blood islands formation in the embryonic mouse hearts.Histochemistry and cell biology · 2009Article
- The discovery of a source of adult hematopoietic cells in the embryo.Development (Cambridge, England) · 2008Article
- The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation.Cell stem cell · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Until now the allantois has not been considered as a hematopoietic organ. Here we report experimental evidence demonstrating the in situ emergence of both hematopoietic and endothelial precursors in the avian allantoic bud. When the prevascularized allantoic bud from a quail embryo was grafted in the coelom of a chicken host, hematopoietic and endothelial cells later were found in the bone marrow of the host. Because the graft was located at a distance from the limb bud, these cells could reach the bone marrow only by the circulatory pathway. This blood-borne seeding may be accomplished by distinct hematopoietic and endothelial precursors, or by hemangioblasts, the postulated common precursors of these two lineages; we consider the latter interpretation more likely. We also show by reverse transcription-PCR that the allantois region expresses very early the GATA genes involved in hematopoiesis and some beta-globin chain genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.