ArticleAmerican journal of human genetics1998
Mitochondrial control-region sequence variation in aboriginal Australians.
Article in American journal of human genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 72 citations in OpenAlex.
- Aboriginal Australian mitochondrial genome variation - an increased understanding of population antiquity and diversity.Scientific reports · 2017Article
- Mitochondrial DNA diversity of present-day Aboriginal Australians and implications for human evolution in Oceania.Journal of human genetics · 2017Article
- Human settlement history between Sunda and Sahul: a focus on East Timor (Timor-Leste) and the Pleistocenic mtDNA diversity.BMC genomics · 2015Article
- The role of genetic drift in shaping modern human cranial evolution: a test using microevolutionary modeling.International journal of evolutionary biology · 2011Article
- Whole-genome genetic diversity in a sample of Australians with deep Aboriginal ancestry.American journal of human genetics · 2010Article
- Revealing the prehistoric settlement of Australia by Y chromosome and mtDNA analysis.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- A comprehensive analysis of microsatellite diversity in Aboriginal Australians.Journal of human genetics · 2007Article
- Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines.Genome research · 2003Article
- Mitochondrial DNA sequences in ancient Australians: Implications for modern human origins.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Independent histories of human Y chromosomes from Melanesia and Australia.American journal of human genetics · 2001Article
- Why hunter-gatherer populations do not show signs of pleistocene demographic expansions.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Peopling of Sahul: mtDNA variation in aboriginal Australian and Papua New Guinean populations.American journal of human genetics · 1999Article
- Mitochondrial DNA analysis: polymorphisms and pathogenicity.Journal of medical genetics · 1999Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mitochondrial D-loop hypervariable segment 1 (mt HVS1) between nucleotides 15997 and 16377 has been examined in aboriginal Australian people from the Darling River region of New South Wales (riverine) and from Yuendumu in central Australia (desert). Forty-seven unique HVS1 types were identified, varying at 49 nucleotide positions. Pairwise analysis by calculation of BEPPI (between population proportion index) reveals statistically significant structure in the populations, although some identical HVS1 types are seen in the two contrasting regions. mt HVS1 types may reflect more-ancient distributions than do linguistic diversity and other culturally distinguishing attributes. Comparison with sequences from five published global studies reveals that these Australians demonstrate greatest divergence from some Africans, least from Papua New Guinea highlanders, and only slightly more from some Pacific groups (Indonesian, Asian, Samoan, and coastal Papua New Guinea), although the HVS1 types vary at different nucleotide sites. Construction of a median network, displaying three main groups, suggests that several hypervariable nucleotide sites within the HVS1 are likely to have undergone mutation independently, making phylogenetic comparison with global samples by conventional methods difficult. Specific nucleotide-site variants are major separators in median networks constructed from Australian HVS1 types alone and for one global selection. The distribution of these, requiring extended study, suggests that they may be signatures of different groups of prehistoric colonizers into Australia, for which the time of colonization remains elusive.
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