Evidence map›Paper›PMID 9462491›Full record

Trial reportJournal of general internal medicine1998

Risks of complication following thyroidectomy.

M R Burge, T M Zeise, M W Johnsen, M J Conway, C R Qualls

Open access · bronzeAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Journal of general internal medicine, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Anaplastic Thyroid Carcinoma, Version 2.2015.Journal of the National Comprehensive Cancer Network : JNCCN · 2015
    Guideline
  2. Article
  3. Article
  4. Preoperative vitamin D deficiency is associated with increased risk of postoperative hypocalcemia after total thyroidectomy.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021
    Article
  5. Review
  6. Population-Based Assessment of Complications Following Surgery for Thyroid Cancer.The Journal of clinical endocrinology and metabolism · 2017
    Article
  7. DOES PRE-OPERATIVE VITAMIN D DEFICIENCY PREDICT POSTOPERATIVE HYPOCALCEMIA AFTER THYROIDECTOMY?Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2017
    Article
  8. Article
  9. Article
  10. Article
  11. Total thyroidectomy is associated with increased prevalence of permanent hypoparathyroidism.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Article
  12. Report from the OECI Oncology Days 2014.Ecancermedicalscience · 2014
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Know thy surgeon: the importance of surgeon-specific information.Journal of general internal medicine · 1998
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M R BurgeDepartment of Medicine, University of New Mexico School of Medicine, Albuquerque 87131, USA.
T M Zeise
M W Johnsen
M J Conway
C R Qualls
University of New Mexico · USLovelace Medical Center · US

Funding

ZUNI KIDNEY PROJECT STUDY I--POPULATION BASED SURVEY OF RENAL DISEASEM01RR000997 · NCRR · UNIVERSITY OF NEW MEXICO · PI ROLDAN, CARLOS A · 1985 to 2010
$30.0M
NCRR NIH HHS 5M01-RR00997
6 · The paper itself

Abstract

objectiveBecause hypoparathyroidism is a serious complication of thyroidectomy, we attempted to elucidate factors determining the risk of this postoperative outcome.

settingFour tertiary care hospitals in Albuquerque, New Mexico. PATIENTS: A retrospective study of 142 patients who underwent total or subtotal thyroidectomy between 1988 and 1995. MEASUREMENTS AND MAIN

resultsPermanent hypoparathyroidism was defined as hypocalcemic symptoms plus a requirement for oral vitamin D or calcium 6 months after thyroidectomy. Factors analyzed to determine their contribution to the risk of persistent postoperative hypoparathyroidism were the indication for thyroidectomy, performance of a preoperative thyroid needle biopsy, type of surgery, postoperative pathology, presence and stage of thyroid carcinoma, resident surgeon involvement, and specialty of the surgeon performing the procedure. Surgical specialty and stage of thyroid carcinoma were independent risk factors for persistent postoperative hypoparathyroidism by multivariate analysis. Nine (29%) of 31 patients who had thyroidectomy by otolaryngologists met criteria for permanent hypoparathyroidism, and 6 (5%) of 111 patients who had thyroidectomy by general surgeons met the same criteria (p < .001). Adjustment for the effect of stage did not eliminate the effect of specialty (p = .006), and adjustment for the effect of specialty did not eliminate the effect of stage (p = .02), on the occurrence of postoperative hypoparathyroidism.

conclusionsWe conclude from our data that patients undergoing thyroidectomy by an otolaryngologist may be at a higher risk of permanent postoperative hypoparathyroidism than patients who undergo thyroidectomy by a general surgeon. This may reflect differences in case selection or surgical approach or both.

Indexed as

Postoperative ComplicationsAdministration, OralAdultBiopsy, NeedleCalciumCarcinomaFemaleHumansHypocalcemiaHypoparathyroidismMaleNew MexicoRetrospective StudiesRisk FactorsThyroidectomyThyroid NeoplasmsCalciumVitamin D

Identifiers

PMID9462491
PMCPMC1496901
OpenAlexW1980815605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.