Evidence map›Paper›PMID 9457432›Full record

ReviewClinical microbiology reviews1998

Diarrheagenic Escherichia coli.

J P Nataro, J B Kaper

Erratum issuedAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1,767 papers.

0numbers the graph read from it
0cells of the map it votes in
1,767citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,767 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Global expression profile of enterohemorrhagic Escherichia coli O157:H7 in phagosome of murine macrophages.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  8. Article
  9. Article
  10. Surveillance of enteropathogenicJournal of medical microbiology · 2026
    Article
  11. Metagenomic Profiling of DiarrheagenicCurrent issues in molecular biology · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Molecular Characterization of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

1,707 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors.

J P NataroDepartment of Medicine, University of Maryland School of Medicine, Baltimore 21201, USA. jnataro@umaryland.edu
J B Kaper

Funding

Virulence in Enteroaggregative Escherichia coliR01AI033096 · NIAID · UNIVERSITY OF VIRGINIA · PI NATARO, JAMES P. · 1996 to 2014
$6.6M
Molecular Genetics of Enteropathogenic E. Coli AdhesionR37AI021657 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 2004 to 2013
$4.8M
MOLECULAR GENETICS OF ENTEROPATHOGENIC E COLI ADHESIONR01AI021657 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 1989 to 2003
$1.4M
NOVEL PROTEINS SECRETED BY E COLI 0157--H7R01AI041325 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 1996 to 2000
$243k
MOLECULAR GENETICS OF ENTEROPATHOGENIC E. COLI ADHESIONR22AI021657 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 1986 to 1991
–
ADHERENCE IN ENTEROAGGREGATIVE E. COLIR29AI033096 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI NATARO, JAMES P. · 1992 to 1996
–
NIAID NIH HHS AI-21657NIAID NIH HHS AI-33096NIAID NIH HHS AI-41325NIAID NIH HHS R01 AI021657NIAID NIH HHS R01 AI033096NIAID NIH HHS R37 AI021657
6 · The paper itself

Abstract

Escherichia coli is the predominant nonpathogenic facultative flora of the human intestine. Some E. coli strains, however, have developed the ability to cause disease of the gastrointestinal, urinary, or central nervous system in even the most robust human hosts. Diarrheagenic strains of E. coli can be divided into at least six different categories with corresponding distinct pathogenic schemes. Taken together, these organisms probably represent the most common cause of pediatric diarrhea worldwide. Several distinct clinical syndromes accompany infection with diarrheagenic E. coli categories, including traveler's diarrhea (enterotoxigenic E. coli), hemorrhagic colitis and hemolytic-uremic syndrome (enterohemorrhagic E. coli), persistent diarrhea (enteroaggregative E. coli), and watery diarrhea of infants (entero-pathogenic E. coli). This review discusses the current level of understanding of the pathogenesis of the diarrheagenic E. coli strains and describes how their pathogenic schemes underlie the clinical manifestations, diagnostic approach, and epidemiologic investigation of these important pathogens.

Indexed as

Escherichia coli InfectionsDiarrheaHumans

Identifiers

PMID9457432
PMCPMC121379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.