Evidence map›Paper›PMID 9457429›Full record

ReviewClinical microbiology reviews1998

Microbiological and clinical aspects of infection associated with Stenotrophomonas maltophilia.

M Denton, K G Kerr

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05193058 (Description of Lung Transplant Patients With Microbiologically Documented Stenotrophomonas Maltophilia Pneumonia and Impact of Treatment on Outcome), which is not on this map. Cited by 283 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
283citing papers in PubMed, 3 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05193058 unknown statusnot on this mapstarted 2021, after this paper: background citation

Description of Lung Transplant Patients With Microbiologically Documented Stenotrophomonas Maltophilia Pneumonia and Impact of Treatment on Outcome

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2021 to 2023Enrolled70ConditionsTransplantation Infection
3 · Its place in the literature

Who cites it

283 citing papers in PubMed, 3 syntheses or guidelines pooled it, 849 citations in OpenAlex.

  1. Hemorrhagic Pneumonia Caused byMedicina (Kaunas, Lithuania) · 2024
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Shifting Epidemiology ofJournal of clinical medicine · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Frontiers in microbiology · 2026
    Article
  11. Article
  12. Article
  13. The Other Face ofAntibiotics (Basel, Switzerland) · 2026
    Article
  14. Genetic Diversity ofPathogens (Basel, Switzerland) · 2025
    Article
  15. ASM case reports · 2025
    Article
  16. Predictors of mortality and progression from colonization to Stenotrophomonas maltophilia bloodstream infection in hematologic disorders: a single-center retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

223 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M DentonDepartment of Microbiology, University of Leeds, United Kingdom.
K G Kerr
University of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gram-negative bacterium Stenotrophomonas maltophilia is increasingly recognized as an important cause of nosocomial infection. Infection occurs principally, but not exclusively, in debilitated and immunosuppressed individuals. Management of S. maltophilia-associated infection is problematic because many strains of the bacterium manifest resistance to multiple antibiotics. These difficulties are compounded by methodological problems in in vitro susceptibility testing for which there are, as yet, no formal guidelines. Despite its acknowledged importance as a nosocomial pathogen, little is known of the epidemiology of S. maltophilia, and although it is considered an environmental bacterium, its sources and reservoirs are often not readily apparent. Molecular typing systems may contribute to our knowledge of the epidemiology of S. maltophilia infection, thus allowing the development of strategies to interrupt the transmission of the bacterium in the hospital setting. Even less is known of pathogenic mechanisms and putative virulence factors involved in the natural history of S. maltophilia infection and this, coupled with difficulties in distinguishing colonization from true infection, has fostered the view that the bacterium is essentially nonpathogenic. This article aims to review the current taxonomic status of S. maltophilia, and it discusses the laboratory identification of the bacterium. The epidemiology of the organism is considered with particular reference to nosocomial outbreaks, several of which have been investigated by molecular typing techniques. Risk factors for acquisition of the bacterium are also reviewed, and the ever-expanding spectrum of clinical syndromes associated with S. maltophilia is surveyed. Antimicrobial resistance mechanisms, pitfalls in in vitro susceptibility testing, and therapy of S. maltophilia infections are also discussed.

Indexed as

Anti-Bacterial AgentsGram-Negative Bacterial InfectionsHumansXanthomonasAnti-Bacterial Agents

Identifiers

PMID9457429
PMCPMC121376
OpenAlexW2155246554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.