ArticleThe Journal of cell biology1998
Thy-1 is a component common to multiple populations of synaptic vesicles.
Article in The Journal of cell biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 62 citations in OpenAlex.
- The Role of the Immunoglobulin Superfamily of Cell Adhesion Molecules in Intellectual Disability.Cells · 2026Review
- Machine learning-driven identification of exosome- related biomarkers in head and neck squamous cell carcinoma.Frontiers in immunology · 2025Article
- Characterization of Central and Nasal Orbital Adipose Stem Cells and their Neural Differentiation Footprints.Current stem cell research & therapy · 2024Article
- Circadian rhythm disruptions associated with opioid use disorder in synaptic proteomes of human dorsolateral prefrontal cortex and nucleus accumbens.Molecular psychiatry · 2023Article
- N-glycoproteomics of brain synapses and synaptic vesicles.Cell reports · 2023Article
- CD90 affects the biological behavior and energy metabolism level of gastric cancer cells by targeting the PI3K/AKT/HIF-1α signaling pathway.Oncology letters · 2021Article
- Cancer Stem Cell Functions in Hepatocellular Carcinoma and Comprehensive Therapeutic Strategies.Cells · 2020Review
- Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid.Molecular & cellular proteomics : MCP · 2019Article
- Thy-1 as an Integrator of Diverse Extracellular Signals.Frontiers in cell and developmental biology · 2019Review
- Glycosylphosphatidylinositol-Anchored Immunoglobulin Superfamily Cell Adhesion Molecules and Their Role in Neuronal Development and Synapse Regulation.Frontiers in molecular neuroscience · 2017Review
- A reduction in CD90 (THY-1) expression results in increased differentiation of mesenchymal stromal cells.Stem cell research & therapy · 2016Article
- Restless legs syndrome: pathophysiology and treatment.Current treatment options in neurology · 2014Article
- The Proteome of the Murine Presynaptic Active Zone.Proteomes · 2014Review
- Gender-specific regulation of tyrosine hydroxylase in thymocyte differentiation antigen-1 knockout mice.Journal of neuroscience research · 2012Article
- Proteomic analysis of the presynaptic active zone.Experimental brain research · 2012Review
- Amyloid-β-induced synapse damage is mediated via cross-linkage of cellular prion proteins.The Journal of biological chemistry · 2011Article
- Pathophysiology of restless legs syndrome: evidence for iron involvement.Current neurology and neuroscience reports · 2008Review
- Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles.Molecular biology of the cell · 2005Article
- Restless legs syndrome.Current neurology and neuroscience reports · 2005Review
- Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons.Molecular biology of the cell · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Thy-1, a glycosylphosphatidylinositol-linked integral membrane protein of the immunoglobulin superfamily, is a component of both large dense-core and small clear vesicles in PC12 cells. A majority of this protein, formerly recognized only on the plasma membrane of neurons, is localized to regulated secretory vesicles. Thy-1 is also present in synaptic vesicles in rat central nervous system. Experiments on permeabilized PC12 cells demonstrate that antibodies against Thy-1 inhibit the regulated release of neurotransmitter; this inhibition appears to be independent of any effect on the Ca2+ channel. These findings suggest Thy-1 is an integral component of many types of regulated secretory vesicles, and plays an important role in the regulated vesicular release of neurotransmitter at the synapse.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.