ArticleThe Journal of cell biology1998
Isolation of functional Golgi-derived vesicles with a possible role in retrograde transport.
Article in The Journal of cell biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 94 citations in OpenAlex.
- COPI Vesicle and Tubule Formation at the Golgi Complex.Sub-cellular biochemistry · 2026Review
- Revealing Golgi Architecture: Novel Insights Through Light Microscopy.Sub-cellular biochemistry · 2026Review
- Syntaxin-5's flexibility in SNARE pairing supports Golgi functions.Traffic (Copenhagen, Denmark) · 2023Article
- Acute COG complex inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra-Golgi recycling vesicles.Traffic (Copenhagen, Denmark) · 2023Article
- Cell-free Fluorescent Intra-Golgi Retrograde Vesicle Trafficking Assay.Bio-protocol · 2017Article
- Dissecting functions of the conserved oligomeric Golgi tethering complex using a cell-free assay.Traffic (Copenhagen, Denmark) · 2014Article
- Article
- The dynamics of engineered resident proteins in the mammalian Golgi complex relies on cisternal maturation.The Journal of cell biology · 2013Article
- Non-muscle myosin IIA transports a Golgi glycosyltransferase to the endoplasmic reticulum by binding to its cytoplasmic tail.The international journal of biochemistry & cell biology · 2012Article
- Irradiation-induced protein inactivation reveals Golgi enzyme cycling to cell periphery.Journal of cell science · 2012Article
- Golgi and related vesicle proteomics: simplify to identify.Cold Spring Harbor perspectives in biology · 2011Review
- PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking.The Journal of cell biology · 2009Article
- Membrane traffic within the Golgi apparatus.Annual review of cell and developmental biology · 2009Review
- Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association.Molecular biology of the cell · 2007Article
- Rab1 defines a novel pathway connecting the pre-Golgi intermediate compartment with the cell periphery.Molecular biology of the cell · 2006Article
- Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells.The Journal of cell biology · 2005Article
- Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'.Molecular biology of the cell · 2005Article
- Golgi enzymes are enriched in perforated zones of golgi cisternae but are depleted in COPI vesicles.Molecular biology of the cell · 2004Article
- Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function.The Journal of cell biology · 2002Article
- Small cargo proteins and large aggregates can traverse the Golgi by a common mechanism without leaving the lumen of cisternae.The Journal of cell biology · 2001Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Secretory proteins enter the Golgi apparatus when transport vesicles fuse with the cis-side and exit in transport vesicles budding from the trans-side. Resident Golgi enzymes that have been transported in the cis-to-trans direction with the secretory flow must be recycled constantly by retrograde transport in the opposite direction. In this study, we describe the functional characterization of Golgi-derived transport vesicles that were isolated from tissue culture cells. We found that under the steady-state conditions of a living cell, a fraction of resident Golgi enzymes was found in vesicles that could be separated from cisternal membranes. These vesicles appeared to be depleted of secretory cargo. They were capable of binding to and fusion with isolated Golgi membranes, and after fusion their enzymatic contents most efficiently processed cargo that had just entered the Golgi apparatus. Those results indicate a possible role for these structures in recycling of Golgi enzymes in the Golgi stack.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.