ArticleBiophysical journal1998
Precipitation of DNA by polyamines: a polyelectrolyte behavior.
Article in Biophysical journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.
What it found
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Who cites it
98 citing papers in PubMed.
- Translational Entropy-Driven Competitive and Additive Effects on DNA Higher-Order Structure via Ion Exchange Between Cations of Different Valencies.Entropy (Basel, Switzerland) · 2026Review
- Suppression of DNA coffee-ring by compacting agents via adsorption at water/substrate and water/air interfaces.Scientific reports · 2026Article
- Surface-Capped Protein Nanoparticles for Nonviral Gene Delivery.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Alexidine, identified as a Z-DNA inducer by the NanoZ screening platform, acts as a transcriptional regulator.Nucleic acids research · 2026Article
- Solutions of Carboxymethylcellulose with Organic Counterions (I): The Influence of Counterion Properties on the Polymer Structure and Solubility.Macromolecules · 2025Article
- Direct SERS Detection of Nucleic Acids in the Presence of Spermine: A Unified Nanoparticle Platform Allows for the Elucidation of Surface Adsorption Hierarchies.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025Article
- Single-molecule measurements of double-stranded DNA condensation.Biophysical journal · 2025Review
- Reexpansion of charged nanoparticle assemblies in concentrated electrolytes.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- DNA-protamine condensates under low salt conditions: molecular dynamics simulation with a simple coarse-grained model focusing on electrostatic interactions.Nanoscale advances · 2023Article
- Phase Separation of Aqueous Poly(diisopropylaminoethyl methacrylate) upon Heating.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Formation of non-base-pairing DNA microgels using directed phase transition of amphiphilic monomers.Nucleic acids research · 2022Article
- Applicability of the linearized Poisson-Boltzmann theory to contact angle problems and application to the carbon dioxide-brine-solid systems.Scientific reports · 2022Article
- HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating.Viruses · 2022Article
- Self-assembly of protein superstructures by physical interactions under cytoplasm-like conditions.Biophysical journal · 2021Article
- Looping-in complexation and ion partitioning in nonstoichiometric polyelectrolyte mixtures.Science advances · 2021Article
- Article
- Local structure of DNA toroids reveals curvature-dependent intermolecular forces.Nucleic acids research · 2021Article
- Topological defects produce kinks in biopolymer filament bundles.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Assembly and Stability of Simian Virus 40 Polymorphs.ACS nano · 2020Article
- Counterion-Dependent Mechanisms of DNA Origami Nanostructure Stabilization Revealed by Atomistic Molecular Simulation.ACS nano · 2019Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conditions of double-stranded DNA precipitation by the polyamines spermidine and spermine have been determined experimentally and compared to theoretical predictions. The influence of the concentrations of DNA and added monovalent salt, and of the DNA length has been investigated in a systematic manner. Three regimes of DNA concentrations are observed. We clarify the dependence of these regimes on the monovalent salt concentration and on the DNA length. Our observations make possible a rationalization of the experimental results reported in the literature. A comparison of the precipitation conditions of different kinds of polyelectrolytes suggests a general process. Our experimental data are compared to the "ion-bridging" model based on short-range electrostatic attractions. By starting from the spinodal equation, predicted by this model, and using the limiting form of Manning's fractions of condensed counterions, analytical expressions of the precipitation conditions have been found in the three regimes. Experimental and theoretical results are in good agreement.
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