ReviewJournal of anatomy1997
Studies of neurotrophin biology in the developing trigeminal system.
Review in Journal of anatomy, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Multiple glycoforms of TrkA interact with N-cadherin during trigeminal ganglion neurodevelopment.Journal of cell science · 2026Article
- Loss of Elp1 disrupts trigeminal ganglion neurodevelopment in a model of familial dysautonomia.eLife · 2022Article
- Dependence of Neuroprosthetic Stimulation on the Sensory Modality of the Trigeminal Neurons Following Nerve Injury. Implications in the Design of Future Sensory Neuroprostheses for Correct Perception and Modulation of Neuropathic Pain.Frontiers in neuroscience · 2019Article
- Cutaneous neurturin overexpression alters mechanical, thermal, and cold responsiveness in physiologically identified primary afferents.Journal of neurophysiology · 2017Article
- ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism.Development (Cambridge, England) · 2013Article
- Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Article
- EphA4 is necessary for spatially selective peripheral somatosensory topography.Developmental dynamics : an official publication of the American Association of Anatomists · 2010Article
- Developmental changes in brainstem neurons regulating lower airway caliber.Pediatric research · 2009Article
- Postnatal roles of glial cell line-derived neurotrophic factor family members in nociceptors plasticity.Sheng li xue bao : [Acta physiologica Sinica] · 2008Review
- Differential Trk expression in explant and dissociated trigeminal ganglion cell cultures.Journal of neurobiology · 2005Article
- Diverse dependencies of developing Merkel innervation on the trkA and both full-length and truncated isoforms of trkC.Development (Cambridge, England) · 2002Article
- Target specific differentiation of peripheral trigeminal axons in rat-chick chimeric explant cocultures.Brain research. Developmental brain research · 2001Article
- Regulation of neurotrophin-induced axonal responses via Rho GTPases.The Journal of comparative neurology · 2001Article
- Retrograde axonal transport of dopamine beta hydroxylase antibodies by neurons in the trigeminal ganglion.Neurochemical researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The accessibility of the primary sensory neurons of the trigeminal system at stages throughout their development in avian and mammalian embryos and the ease with which these neurons can be studied in vivo has facilitated investigation of several fundamental aspects of neurotrophin biology. Studies of the timing and sequence of action of neurotrophins and the expression of neurotrophins and their receptors in this well characterised neuronal system have led to a detailed understanding of the functions of neurotrophins in neuronal development. The concepts of neurotrophin independent survival, neurotrophin switching and neurotrophin cooperativity have largely arisen from work on the trigeminal system. Moreover, in vitro studies of trigeminal neurons provided some of the first evidence that the neurotrophin requirements of sensory neurons are related to sensory modality. The developing trigeminal system has been studied most extensively in mice and chickens, each of which has particular advantages for understanding different aspects of neurotrophin biology. In this review, I will outline these advantages and describe some of the main findings that have arisen from this work.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.