ArticleJapanese journal of cancer research : Gann1997
Germline mutations of the MEN1 gene in Japanese kindred with multiple endocrine neoplasia type 1.
Article in Japanese journal of cancer research : Gann, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Multiple endocrine neoplasia type 1: analysis of germline MEN1 mutations in the Italian multicenter MEN1 patient database.Endocrine · 2018Article
- Molecular genetics of syndromic and non-syndromic forms of parathyroid carcinoma.Human mutation · 2017Review
- Genetic basis of familial isolated hyperparathyroidism: a case series and a narrative review of the literature.Journal of bone and mineral metabolism · 2014Review
- A MEN1 syndrome with a paraganglioma.European journal of human genetics : EJHG · 2014Article
- Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms.Cancer science · 2011Article
- Multiple endocrine neoplasia type 1.Orphanet journal of rare diseases · 2006Review
- Article
- Novel somatic MEN1 gene alterations in sporadic primary hyperparathyroidism and correlation with clinical characteristics.Journal of endocrinological investigation · 2004Article
- The MEN1 gene and associated diseases: an update.Endocrine pathology · 2001Review
- Large and asymptomatic pancreatic islet cell tumor in a patient with multiple endocrine neoplasia type 1.Endocrine · 2000Article
- Identification of MEN1 gene mutations in families with MEN 1 and related disorders.British journal of cancer · 2000Article
- A newly recognized germline mutation of MEN1 gene identified in a patient with parathyroid adenoma and carcinoma.Endocrine · 2000Article
- Characterization of high-grade neuroendocrine tumors of the lung in relation to menin mutations.Japanese journal of cancer research : Gann · 2000Article
- Characterization of the MEN1 gene product, menin, by site-specific polyclonal antibodies.Japanese journal of cancer research : Gann · 1999Article
- Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disorders.American journal of human genetics · 1998Article
- A large germline deletion of the MEN1 gene in a family with multiple endocrine neoplasia type 1.Japanese journal of cancer research : Gann · 1998Article
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14 authors.
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Abstract
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome. The responsible gene MEN1 has recently been isolated, and its germline mutations have been identified in affected individuals in the United States, Canada and Europe. We screened for MEN1 mutations by direct nucleotide sequencing of all protein-coding regions, and identified five distinct germline mutations in five among six Japanese kindreds with familial MEN1 or familial hyperparathyroidism. The mutations were dispersed across the gene. These findings suggest that, because of the absence of an obvious founder effect, the entire MEN1 gene region should be examined for germline mutations in the probands of MEN1 and related syndromes in Japanese families.
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