ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1998
Multioscillatory circadian organization in a vertebrate, iguana iguana.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 72 citations in OpenAlex.
- Circadian Clock and Body Temperature.Advances in experimental medicine and biology · 2024Review
- Circadian clock organization in the retina: From clock components to rod and cone pathways and visual function.Progress in retinal and eye research · 2023Review
- Translating around the clock: Multi-level regulation of post-transcriptional processes by the circadian clock.Cellular signalling · 2021Review
- Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions.International journal of molecular sciences · 2014Review
- The absence of melanopsin alters retinal clock function and dopamine regulation by light.Cellular and molecular life sciences : CMLS · 2013Article
- Melatonin rhythms in the Australian freshwater crocodile (Crocodylus johnstoni): a reptile lacking a pineal complex?Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2010Article
- Interseasonal variation in the circadian rhythms of locomotor activity and temperature selection in sleepy lizards, Tiliqua rugosa.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2008Article
- Circadian rhythms of locomotor activity and temperature selection in sleepy lizards, Tiliqua rugosa.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2007Article
- Isolation and characterization of melanopsin and pinopsin expression within photoreceptive sites of reptiles.Die Naturwissenschaften · 2006Article
- Circadian rhythms from multiple oscillators: lessons from diverse organisms.Nature reviews. Genetics · 2005Review
- Evolution of photosensory pineal organs in new light: the fate of neuroendocrine photoreceptors.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2003Review
- The Arabidopsis circadian system.The arabidopsis book · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lizard Iguana iguana when kept in constant ambient temperature displays endogenously generated circadian rhythms of body temperature and locomotor activity. Although surgical removal of the parietal eye has only slight effects on overt circadian rhythmicity, subsequent pinealectomy completely abolishes the rhythm of body temperature. However, the rhythm of locomotor activity is only slightly affected by parietalectomy plus pinealectomy. Our results demonstrate that the pineal complex is centrally involved in the generation and control of the circadian rhythm of body temperature but is only marginally involved in locomotor rhythmicity. Plasma melatonin levels are not significantly reduced by parietalectomy, whereas pinealectomy dramatically lowers the level and completely eliminates the circadian rhythm of melatonin in the circulation. Isolated parietal eye, pineal, and retina all synthesize melatonin with robust circadian rhythmicity when maintained for >/=4 d in culture, although in the intact animal all or almost all of the circulating melatonin comes from the pineal. The circadian system of I. iguana is composed of multiple circadian oscillators that reside in different tissues and have specific and different roles.
Indexed as
Identifiers
9437030PMC6792761W2168494680What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.