ArticleMolecular biology of the cell1998
Developmental expression of spectrins in rat skeletal muscle.
Article in Molecular biology of the cell, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 42 citations in OpenAlex.
- A heterozygous 9q34 deletion encompassing SPTAN1 as a cause of distal myopathy.European journal of human genetics : EJHG · 2026Article
- Postsynaptic β1 spectrin maintains NaThe Journal of physiology · 2024Article
- Characteristics of primary Sjögren's syndrome-associated peripheral nervous system lesions.Journal of neurology · 2023Article
- Neuromuscular electrical stimulation promotes development in mice of mature human muscle from immortalized human myoblasts.Skeletal muscle · 2016Article
- Spectrin's chimeric E2/E3 enzymatic activity.Experimental biology and medicine (Maywood, N.J.) · 2015Review
- Differential regulation of apoptosis in slow and fast twitch muscles of aged female F344BN rats.Age (Dordrecht, Netherlands) · 2015Article
- Effects of the plasmid-encoded toxin of enteroaggregative Escherichia coli on focal adhesion complexes.FEMS immunology and medical microbiology · 2011Article
- Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury.The Journal of biological chemistry · 2011Article
- The actin binding domain of βI-spectrin regulates the morphological and functional dynamics of dendritic spines.PloS one · 2011Article
- Characterization and expression of a heart-selective alternatively spliced variant of alpha II-spectrin, cardi+, during development in the rat.Journal of molecular and cellular cardiology · 2010Article
- Sjögren's syndrome--study of autoantigens and autoantibodies.Clinical reviews in allergy & immunology · 2007Review
- Role of an alternatively spliced form of alphaII-spectrin in localization of connexin 43 in cardiomyocytes and regulation by stress-activated protein kinase.Journal of molecular and cellular cardiology · 2007Article
- Sarcolemmal organization in skeletal muscle lacking desmin: evidence for cytokeratins associated with the membrane skeleton at costameres.Molecular biology of the cell · 2002Article
- A nonerythroid isoform of protein 4.1R interacts with components of the contractile apparatus in skeletal myofibers.Molecular biology of the cell · 2000Article
- F-actin is concentrated in nonrelease domains at frog neuromuscular junctions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Mutations in beta-spectrin disrupt axon outgrowth and sarcomere structure.The Journal of cell biology · 2000Article
- Extensive but coordinated reorganization of the membrane skeleton in myofibers of dystrophic (mdx) mice.The Journal of cell biology · 1999Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Skeletal muscle contains spectrin (or spectrin I) and fodrin (or spectrin II), members of the spectrin supergene family. We used isoform-specific antibodies and cDNA probes to investigate the molecular forms, developmental expression, and subcellular localization of the spectrins in skeletal muscle of the rat. We report that beta-spectrin (betaI) replaces beta-fodrin (betaII) at the sarcolemma as skeletal muscle fibers develop. As a result, adult muscle fibers contain only alpha-fodrin (alphaII) and the muscle isoform of beta-spectrin (betaISigma2). By contrast, other types of cells present in skeletal muscle tissue, including blood vessels and nerves, contain only alpha- and beta-fodrin. During late embryogenesis and early postnatal development, skeletal muscle fibers contain a previously unknown form of spectrin complex, consisting of alpha-fodrin, beta-fodrin, and the muscle isoform of beta-spectrin. These complexes associate with the sarcolemma to form linear membrane skeletal structures that otherwise resemble the structures found in the adult. Our results suggest that the spectrin-based membrane skeleton of muscle fibers can exist in three distinct states during development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.