ArticleCell1997
Molecular structure of a functional Drosophila centromere.
Article in Cell, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
114 citing papers in PubMed, 252 citations in OpenAlex.
- The dynamic centromere.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025Review
- QTL identification and characterization of the recombination landscape of the mountain pine beetle (Dendroctonus ponderosae).G3 (Bethesda, Md.) · 2025Article
- Large tandem repeats of grass frog (Rana temporaria) in silico and in situ.BMC genomics · 2025Article
- Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression.PLoS biology · 2025Article
- Centromere structure and function: lessons from Drosophila.Genetics · 2023Article
- A genetic basis for facultative parthenogenesis in Drosophila.Current biology : CB · 2023Article
- Review
- Identification and characterization of centromeric sequences inGenome research · 2021Article
- Sequence, Chromatin and Evolution of Satellite DNA.International journal of molecular sciences · 2021Review
- Origins and Evolutionary Patterns of theG3 (Bethesda, Md.) · 2020Article
- Centromeres under Pressure: Evolutionary Innovation in Conflict with Conserved Function.Genes · 2020Review
- Targeted De Novo Centromere Formation in Drosophila Reveals Plasticity and Maintenance Potential of CENP-A Chromatin.Developmental cell · 2020Article
- Genome Size Evolution Differs BetweenG3 (Bethesda, Md.) · 2019Article
- Article
- Islands of retroelements are major components of Drosophila centromeres.PLoS biology · 2019Article
- Evolution of the Drosophila melanogaster Chromatin Landscape and Its Associated Proteins.Genome biology and evolution · 2019Article
- Article
- Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation.The Journal of cell biology · 2018Article
- Variable Rates of Simple Satellite Gains across the Drosophila Phylogeny.Molecular biology and evolution · 2018Article
- Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Centromeres play a critical role in chromosome inheritance but are among the most difficult genomic components to analyze in multicellular eukaryotes. Here, we present a highly detailed molecular structure of a functional centromere in a multicellular organism. The centromere of the Drosophila minichromosome Dp1187 is contained within a 420 kb region of centric heterochromatin. We have used a new approach to characterize the detailed structure of this centromere and found that it is primarily composed of satellites and single, complete transposable elements. In the rest of the Drosophila genome, these satellites and transposable elements are neither unique to the centromeres nor present at all centromeres. We discuss the impact of these results on our understanding of heterochromatin structure and on the determinants of centromere identity and function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.