ReviewThe Biochemical journal1998
Signal transduction by the Wnt family of ligands.
Review in The Biochemical journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
140 citing papers in PubMed, 1 synthesis or guideline pooled it, 468 citations in OpenAlex.
- Tooth agenesis and orofacial clefting: genetic brothers in arms?Human genetics · 2016Pooled it
- Roles of β-catenin protein in non-small cell lung cancer (Review).Oncology letters · 2025Review
- The Synergistic Role of ApoE4 and GSK3β in Alzheimer's Disease: Pathological Mechanisms and Therapeutic Implications.Molecular neurobiology · 2025Review
- Exosomal tsRNA-Gly-5-0007 may be used as a diagnostic marker for colorectal cancer.Scientific reports · 2025Article
- GSK-3β and mTOR Phosphorylation Mediate the Reversible Regulation of Hypomagnetic Field on Adult Neural Stem Cell Proliferation.The European journal of neuroscience · 2025Article
- WNT ligands in non-small cell lung cancer: from pathogenesis to clinical practice.Discover oncology · 2023Review
- Organ and cell-specific biomarkers of Long-COVID identified with targeted proteomics and machine learning.Molecular medicine (Cambridge, Mass.) · 2023Article
- Modeling of Neurodegenerative Diseases: 'Step by Step' and 'Network' Organization of the Complexes of Model Systems.International journal of molecular sciences · 2022Review
- Wnt2b and Wnt5a expression is highly associated with M2 TAMs in non‑small cell lung cancer.Oncology reports · 2022Article
- Article
- Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma Treatment.Diagnostics (Basel, Switzerland) · 2021Review
- Identification of the prognostic value of a 2-gene signature of the WNT gene family in UCEC using bioinformatics and real-world data.Cancer cell international · 2021Article
- The pancancer landscape of Wnt family expression reveals potential biomarkers in urinary system tumors.Cancer gene therapy · 2021Article
- Is There Justification to Treat Neurodegenerative Disorders by Repurposing Drugs? The Case of Alzheimer's Disease, Lithium, and Autophagy.International journal of molecular sciences · 2020Review
- Wnt signaling regulates the proliferation potential and lineage commitment of human umbilical cord derived mesenchymal stem cells.Molecular biology reports · 2020Article
- A Novel Homozygous Frameshift Mutation inFrontiers in pediatrics · 2019Article
- miR-1 and miR-802 regulate mesenchymal-epithelial transition during kidney development by regulating Wnt-4/β-catenin signaling.American journal of translational research · 2019Article
- Expression of the Wnt ligands gene family and its relationship to prognosis in hepatocellular carcinoma.Cancer cell international · 2019Article
- Molecular characterization of Wnt pathway and function of β-catenin overexpression in medulloblastoma cell lines.Cytotechnology · 2018Article
- Discoidin domain receptor 1: New star in cancer-targeted therapy and its complex role in breast carcinoma.Oncology letters · 2018Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Wnt genes encode a large family of secreted polypeptides that mediate cell-cell communication in diverse developmental processes. The loss or inappropriate activation of Wnt expression has been shown to alter cell fate, morphogenesis and mitogenesis. Recent progress has identified Wnt receptors and components of an intracellular signalling pathway that mediate Wnt-dependent transcription. This review will highlight this 'core' Wnt signal-transduction pathway, but also aims to reveal the potential diversity of Wnt signalling targets. Particular attention will be paid to the overlap between developmental biology and oncogenesis, since recent progress shows Wnt signalling forms a paradigm for an interdisciplinary approach.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.